DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and acsf3

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_021329817.1	Gene:	acsf3 / 562292	ZFINID:	ZDB-GENE-121026-3	Length:	579	Species:	Danio rerio

Alignment Length:	597	Identity:	126/597 - (21%)
Similarity:	225/597 - (37%)	Gaps:	117/597 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DLNGNPATSYDPVQKVWSGCSRHSLYNEELTVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQ 67
            ||..:||.:     ||....||...|.:::.:                 :.|:.:.  |...:.:
Zfish    42 DLINSPAGA-----KVAPVFSRAPAYGDKVAI-----------------MDHSGSH--TYHSLYK 82

  Fly    68 NAAKIGCYLRDQGFKKETDLVG-----LMARNSTHVGA--LAYGCLFNGTPFHAVNP--NLEHNT 123
            |:..:..::......:..||.|     |.|.::::..|  .::.|.....|.:..:|  .||: .
Zfish    83 NSKILAGHITKALTCQSGDLQGKRISFLCANDASYTVAQWASWMCGGIAVPLYRKHPLSELEY-V 146

  Fly   124 ISSLYKITRPRILCCDTADYEKIKDIGASLGALIITVNGKLPGVISVADILQNPLPDDYEPAQFQ 188
            ||.    ::..:|....:..:.::.:...||...:    |||...|..:..|. ||:|    ...
Zfish   147 ISD----SQSSLLVAGQSFVDTLEPLAQKLGLPCL----KLPATSSQFEDTQT-LPED----MIS 198

  Fly   189 RGVDRTMAILCSSGTTGTPKAVTLSNSRKLFEMHSYLGS------DDVQYAPSTLDWLTGLITLV 247
            ...:|...::.:|||||.||.|..::| .|..|...|.|      |||......|..:.|::..:
Zfish   199 DWAERPAMLIYTSGTTGRPKGVLHTHS-SLQAMVQGLVSEWAWHKDDVILHTLPLHHVHGIVNKL 262

  Fly   248 TAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAGG 312
            ...::.....|....||..   .:.||...|.:.|.|..:|:     .|...||.......|
Zfish   263 MCPLWVGATCIMLPDFSAQ---KVWEQLICSKSPMVNVFMAV-----PTIYSKLIEYYDQHF--- 316

  Fly   313 HCLVATLKKMQSFLH------------GSG----------------ILRNAYGLTEVGTLVSYNY 349
                 |..::|.|:.            ||.                :|...||:||:|..:|.:|
Zfish   317 -----TQPQVQDFIRAVCKERIRLMVSGSAALPQPVLERWAEITDHVLLERYGMTEIGMALSNSY 376

  Fly   350 DTQSKPTSVG--------RLMANIRVKIVDSSGQ-------LQGPKGLGEILCHNGQPWSGYVGN 399
            .....|.:||        |:|.|..:.|.:.:.:       |:|.:  ||:|......:..|...
Zfish   377 KGPRVPGAVGVPLPGVEVRIMMNSSIVIAEGTSKGTQVKAGLEGKE--GELLVRGSSVFQKYWNK 439

  Fly   400 PLATAEMRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCV 464
            |..|.|......|:.|||...:.:..|..:.....|::|..|......:||..:...||:.:|.|
Zfish   440 PQETEESFTEDRWFKTGDTALYRDGVYWIMGRTSVDIIKSGGYKISALDVERHLLAHPDITDVAV 504

  Fly   465 FGIFRETEGDAAAASVVLRSGSKLDPKHVEQYVRKNVSVQFKHLHGGVQFVPQLAKSANGKVNRQ 529
            .|....|.|....|.|.:|.|..:....::.:.|::::..  .:..|:..|..:.::..||||::
Zfish   505 IGAPDATWGQKVTAVVQMRKGKTMILSDLKAWAREHMASY--SIPTGLILVEDMPRNQMGKVNKK 567

  Fly   530 AVKAAYLRDATQ 541
            .:...:....:|
Zfish   568 DLLRQFFPGGSQ 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	118/574 (21%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	114/533 (21%)
acsf3	XP_021329817.1	MCS	64..566	CDD:213307	115/555 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900