DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and slc27a1b

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001070716.1	Gene:	slc27a1b / 553512	ZFINID:	ZDB-GENE-061013-672	Length:	648	Species:	Danio rerio

Alignment Length:	520	Identity:	112/520 - (21%)
Similarity:	209/520 - (40%)	Gaps:	80/520 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTH 97
            |:..:..:::...|::...:..:.....:..::.:.:..:..::..||: :..|:|.:...:...
Zfish    79 TIPSLFAQRVALHPEKAALVDESSGEVWSFSELDRRSNAVAQWVLAQGW-RSGDVVAIFMESRPQ 142

  Fly    98 VGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALIITVNG 162
            :.||..|....|.....:|.||..:::.....::....:.......:.:.::..||.:|.:...|
Zfish   143 MVALWLGMAKVGVEPALINFNLRRDSLIHCMGVSGACGMVFGAELLDVVLEVRESLRSLSLFSCG 207

  Fly   163 KLPG----VISVADI--LQNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAVTLSNSR----K 217
            ..|.    .:|.||:  |.:..|:........:|.:..:..:.:|||||.|||..:.:||    .
Zfish   208 SAPAEMLDSLSAADLDALLSKSPETPPAVAHNKGFNDRLFYIYTSGTTGLPKAAIVVHSRYYRIA 272

  Fly   218 LFEMHSY-LGSDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTI 281
            .|..:|: |..|||.|....|....|.|..|...:...:.::....||.:.|.|.|    |.:..
Zfish   273 AFSYYSFGLQPDDVVYCCLPLYHSAGNIIGVGQCLLHGLTVVIRRKFSASRFWDDC----VKYNC 333

  Fly   282 MANSHVAMLANCPKTSAQKLR---SLKHLLFAGGHCLVATLKKMQSFLHGSGILR--NAYGLTEV 341
            ....::..:  |....:|.:|   ||..:..|.|:.|...:  .:||:....:.|  ..||.||.
Zfish   334 TVVQYIGEI--CRYLLSQPVRPSESLHRVRVAMGNGLRPNV--WESFMKRFSVKRIGEFYGATEC 394

  Fly   342 GTLVSYNYDTQSKPTSVGRLMAN---------IRVKIVDSSGQ--LQGPKGLGEILCHNGQP--- 392
            ...:: |.|.:     ||....|         ||:...|....  ::..:||. :.|..|:|
Zfish   395 NCSLA-NMDNK-----VGACGFNSVVLPSVYPIRLLRADEDTMELIRDSRGLC-VPCKPGEPGII 452

  Fly   393 ------------WSGYVGNPLATAE--------MRDSAGWYHTGDVGYFDEDHYLHIVERKKDML 437
                        :.|| .|..||::        ..|||  |.:||:...||..|::..:|..|..
Zfish   453 VGRINPQDPLRRFDGY-ANEEATSKKISHNVFRKGDSA--YVSGDLMVMDELGYVYFRDRGGDTF 514

  Fly   438 KYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSGSKLDPKHV---EQYVR 498
            ::.|......|||.|::.:....:|.|:|: ....||.|..|::.       ||::|   |.::|
Zfish   515 RWRGENVSTTEVEGVLSALLKQTDVAVYGVSVPGVEGKAGMAAIA-------DPENVFDCETFLR 572

Fly 499 498
Zfish 573 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	112/520 (22%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	110/502 (22%)
slc27a1b	NP_001070716.1	PRK08279	60..648	CDD:236217	112/520 (22%)
slc27a1b	NP_001070716.1	AFD_class_I	103..613	CDD:302604	110/496 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583000
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840