DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and slc27a1a

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001013555.1	Gene:	slc27a1a / 541410	ZFINID:	ZDB-GENE-050320-112	Length:	647	Species:	Danio rerio

Alignment Length:	526	Identity:	113/526 - (21%)
Similarity:	195/526 - (37%)	Gaps:	96/526 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HSLYNEELTVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVG 89
            |.:.|.. |:..|..:.:.|.|.:...:........|..|:.|.:..:..:...||: ...|:|.
Zfish    70 HYMRNRN-TIPSIFAQTVARHPDKPALVYEATGETWTFSQLDQISNAVAHWALSQGW-TSGDVVA 132

  Fly    90 LMARNSTHVGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPR--ILCCDTADYEKIKDIGAS 152
            |...:.....||..|....|.....:|.||..:::.....::..|  :...:.||  .:.::..|
Zfish   133 LFMESRPLQVALWLGLAKVGVEAALINFNLRRDSLLHCVGVSASRGIVFGAELAD--AVSEVSHS 195

  Fly   153 LGALIITVN-GKLPGVISVA------DILQNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAV 210
            |...::..: |.|...:..|      |.:....|.........:|.:..:..:.:|||||.|||.
Zfish   196 LSQTMVRFSTGDLKPDLMAALKCQPLDPILASAPRHPPSCTVSKGFNDHLFYIYTSGTTGLPKAA 260

  Fly   211 TLSNSR----KLFEMHSY-LGSDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHFLD 270
            .:.:||    ..|...|: :..||:.|....|....|.|..|...:...:.::....||.:.|.:
Zfish   261 IVVHSRYYRIAAFGYLSFRMRPDDIIYDCLPLYHSAGNIMGVGQCLIHGLTVVVKRKFSASRFWE 325

  Fly   271 ICEQH---------EVSWTIMA-------NSHVAMLA--NCPKTSAQ-------KLRSLKHLLFA 310
            .|.:|         |:...::|       ..|...||  |..:.|..       :::.:.....|
Zfish   326 DCIKHNCTVVQYIGEICRYLLAQPVRPSERQHRVRLAVGNGLRPSVWEAFVERFRVKQIGEFYGA 390

  Fly   311 GG-HCLVATLK-KMQSFLHGSGILRNAYGLTEVGTLVSYNYDTQSKPTSVGRLMANIRVKIVDSS 373
            .| :|.:|.:. |:.:....|.||.|.|.:    .||..|.:|          |..:|.|
Zfish   391 TGCNCSIANMDGKVGACGFNSRILPNVYPI----RLVKVNEET----------MELVRDK----- 436

  Fly   374 GQLQGPKGLGEILCHNGQP---------------WSGYVGNPLATAEM-------RDSAGWYHTG 416
                  :||. :.|..|:|               :.||........::       .|||  |.:|
Zfish   437 ------QGLC-VSCRPGEPGLLVGRINQQDPLRRFDGYASQEATRKKIAYNVFRKNDSA--YLSG 492

  Fly   417 DVGYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASV 480
            ||...||..|::..:|..|..::.|......|||..::.:....:|.|||: ....||.|..|::
Zfish   493 DVLVMDELGYMYFRDRSGDTFRWKGENVSTTEVEGTLSGLLRQTDVAVFGVNVPGVEGKAGMAAI 557

  Fly   481 VLRSGS 486
            ...:||
Zfish   558 ADSTGS 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	113/526 (21%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	107/500 (21%)
slc27a1a	NP_001013555.1	PRK08279	75..647	CDD:236217	111/521 (21%)
slc27a1a	NP_001013555.1	AFD_class_I	101..612	CDD:302604	107/494 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840