DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and Acsf3

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_574249.5	Gene:	Acsf3 / 498962	RGDID:	1586037	Length:	583	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	118/514 - (22%)
Similarity:	198/514 - (38%)	Gaps:	92/514 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 GCYLRDQGFKKETDLVGLMARNSTHVGALAYGCLFNG---TPFHAVNPNLEHNTISSLYKITRPR 134
            ||.:.|    .:.:.|..:..|........:....:|   .|.:..:|..:   :....:.:|..
  Rat    87 GCKVGD----LQEERVSFLCSNDVSYVIAQWASWMSGGVAVPLYRKHPEAQ---LEYFIQDSRSS 144

  Fly   135 ILCCDTADYEKIKDIGASLGALIITVNGKLPGVISVADILQNPLPDDYEPAQFQRGVDRTMAILC 199
            ::.......|::..:...||..::.:.   |.|...|  .:.|:.   :|.|.:...||...|..
  Rat   145 VVVVGQEYLERLSPLAQRLGVPLLPLT---PAVYHGA--AEKPIE---QPIQEREWRDRGAMIFY 201

  Fly   200 SSGTTGTPKAVTLSNSRKLFE-----MHSYLGS-DDVQYAPSTLDWLTGLI-----------TLV 247
            :|||||.||. .||..|.|..     :||:..: :||......|..:.|::           |.|
  Rat   202 TSGTTGRPKG-ALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLHHVHGVVNKLLCPLWVGATCV 265

  Fly   248 TAAVFGT----VRLISSE-----MFST-----AHFLDICEQHEVSWTIMANSHVA--MLANCPKT 296
            ....|..    .:.:|||     ||..     :..||..::|      ...|||.  :.|.|
  Rat   266 MLPEFSAQQVWEKFLSSEAPQINMFMAVPTIYSKLLDYYDRH------FTQSHVQDFVRAVC--- 321

  Fly   297 SAQKLRSLKHLLFAGGHCL-VATLKKMQSFLHGSG-ILRNAYGLTEVGTLVSYNYDTQSKPTSVG 359
             .:::|    |:.:|...| |..|:|.:|   .:| .|...||:||:|..:|........|.|||
  Rat   322 -KERIR----LMVSGSAALPVPLLEKWKS---ATGHTLLERYGMTEIGMALSNPLTEARVPGSVG 378

  Fly   360 RLMANIRVKIVD------------SSGQLQGPK---GL----GEILCHNGQPWSGYVGNPLATAE 405
            ..:..:.|:||.            :.|.::|.|   |.    ||:|......:..|...|..|..
  Rat   379 TPLPGVEVRIVSENPQKGSSYTIHAEGNMRGTKVTPGFEEKEGELLVKGPSVFQEYWDKPEETKS 443

  Fly   406 MRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGIFRE 470
            .....||:.|||...|.:|.|........|::|..|......|:|..:...|.:.:|.|.|:...
  Rat   444 AFTPDGWFRTGDTAVFKDDRYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDM 508

  Fly   471 TEGDAAAASVVLRSGSKLDPKHVEQYVRKNVSVQFKHLHGGVQFVPQLAKSANGKVNRQ 529
            |.|....|.|.|:.|..|..:.::::.| .|...:. :...:..|..:.::..||||::
  Rat   509 TWGQRVTAVVALQEGHSLSHRDLKEWAR-GVLAPYA-VPSELLLVEAIPRNQMGKVNKK 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	118/514 (23%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	116/510 (23%)
Acsf3	XP_574249.5	CaiC	49..572	CDD:223395	118/514 (23%)
Acsf3	XP_574249.5	MCS	55..564	CDD:213307	117/511 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900