Protein Alignment Acsx2 and SLC27A1

DIOPT Version :10

• Sequence 1: NP_650830.1
• Gene: Acsx2 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 129/563 - (22%)
• Similarity: 223/563 - (39%)
• Gaps: 93/563 - (16%)

  Fly    33 TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTH 97
            |:.:|....:||||:|:..:........|..|:...:..:....|..|| ...|:|.:.......
Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGF-APGDVVAIFLEGRPE 140

  Fly    98 VGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALIITVNG 162
            ...|..|....|.....:|.||..          .|...|..|:. .|....|..:.|.:..|:|
Human   141 FVGLWLGLAKAGMEAALLNVNLRR----------EPLAFCLGTSG-AKALIFGGEMVAAVAEVSG 194

  Fly   163 KL--------------PGVISVADILQNPLPDDYEPAQF----QRGVDRTMAILCSSGTTGTPKA 209
            .|              .|::....:| :||..:...|..    .:|:|..:..:.:|||||.|||
Human   195 HLGKSLIKFCSGDLGPEGILPDTHLL-DPLLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKA 258

  Fly   210 VTLSNSR----KLFEMHSY-LGSDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHFL 269
            ..:.:||    ..|..|:| :.:.||.|....|....|.|..|...:...:.::..:.||.:.|.
Human   259 AIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFW 323

  Fly   270 DICEQHEVSWTIMANSHVAMLA--------NCPKTSAQKLRSLK---HLLFAGGHCLVATLKKMQ 323
            |.|.::  :.||....|..:|.        .|.....|.:|..:   .:..|.|:.|...:  .:
Human   324 DDCIKY--NCTINGVRHCRLLCLVVQYIGEICRYLLKQPVREAERRHRVRLAVGNGLRPAI--WE 384

  Fly   324 SFLHGSGI--LRNAYGLTEVGTLVSYNYDTQSKPTSVG---RLMANI-RVKIV----DSSGQLQG 378
            .|....|:  :...||.||....:: |.|  .|..|.|   |::.:: .:::|    |:...|:.
Human   385 EFTERFGVRQIGEFYGATECNCSIA-NMD--GKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRD 446

  Fly   379 PKGLGEILCHNGQP---------------WSGYVGNPLATAEMR-------DSAGWYHTGDVGYF 421
            .:||. |.|..|:|               :.|||.....:.::.       |||  |.:|||...
Human   447 AQGLC-IPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSA--YLSGDVLVM 508

  Fly   422 DEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSG 485
            ||..|::..:|..|..::.|......|||.|::::....:|.|:|: ....||.|..|:|. ...
Human   509 DELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVA-DPH 572

  Fly   486 SKLDPKHVEQYVRKNVSVQFKHLHGGVQFVPQLAKSANGKVNR 528
            |.|||..:.|.::|.::...:.:.  ::.:||:..:...|:.:
Human   573 SLLDPNAIYQELQKVLAPYARPIF--LRLLPQVDTTGTFKIQK 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx2	NP_650830.1	Firefly_Luc_like	51..527	CDD:341237	122/542 (23%)
SLC27A1	XP_011526302.1	Adenylate forming domain, Class I superfamily	101..623	CDD:473059	122/539 (23%)