DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and pdgy

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	534	Identity:	130/534 - (24%)
Similarity:	228/534 - (42%)	Gaps:	51/534 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTHVGA 100
            :.::|..::..:|...:....:.:.|..||...:|.....|:.:...::.|::.:...|......
  Fly    79 EYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPI 143

  Fly   101 LAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKI----KDIGASLGALIITVN 161
            ...|.:..|.....|||....:.|:.....:..:.|....:.:..:    |.:|..:...::..:
  Fly   144 ATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTS 208

  Fly   162 GK--LP-GVISVADI--LQNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAVTLSNSRKLFEM 221
            .:  || |.|..:::  .||...:|.: |..:...|..:.:..||||||.||.|.||
  Fly   209 AEEALPEGAIDFSELTSTQNVRYEDLK-APKEASADDMVFLPFSSGTTGLPKGVMLS-------- 264

  Fly   222 HSYLGS--DDVQYA------------PSTLDW--LTGLITLVTAAVFGTVRLISSEMFSTAHFLD 270
            |:.:.|  :.||.:            |..|.:  :.||..::.:.:....||.:...|....|:.
  Fly   265 HNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMR 329

  Fly   271 ICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFA----GGHCLVATLKKMQSFLHGSGI 331
            ..::::.|...:.......:.|.||.:.:....||.::..    |.|.:...|.|..     :.:
  Fly   330 SLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFP-----NTV 389

  Fly   332 LRNAYGLTEVGTLVSYNYDTQSKPTSVGRLMANIRVKIV-----DSSGQLQGPKGLGEILCHNGQ 391
            .:..||:||...:|....:......|.|.|.|:...|||     |:.|  .||:..||:.....|
  Fly   390 FKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSDAKG--VGPRTTGELCVRGPQ 452

  Fly   392 PWSGYVGNPLATAEMRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQM 456
            ..:||:.|..|.........|..:|||.::|||...:|.:|.|:::|..|....|.|:|.|:...
  Fly   453 VMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDH 517

  Fly   457 PDVAEVCVFGIFRETEGDAAAASVVLRSGSKLDPKHVEQYVRKNVSVQFKHLHGGVQFVPQLAKS 521
            |.:.|..||||..|..|:|..|.||||.|.|...:.:..||.:.|: .:|.|.|||.||.::.|:
  Fly   518 PKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVA-HYKKLEGGVIFVDEVPKN 581

  Fly   522 ANGKVNRQAVKAAY 535
            ..||:.|:.:|..:
  Fly   582 PTGKILRRELKEKF 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	130/534 (24%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	126/509 (25%)
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	130/532 (24%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	126/504 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452145
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850