DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11391 and Slc27a6

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001099615.1	Gene:	Slc27a6 / 291582	RGDID:	1311977	Length:	619	Species:	Rattus norvegicus

Alignment Length:	520	Identity:	113/520 - (21%)
Similarity:	209/520 - (40%)	Gaps:	67/520 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HSLYNEELTVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVG 89
            :.|..|.:||........:|||::.|.|...|  ..|...:.:.:.::...|.:....|..|:|.
  Rat    47 YKLRGELVTVLDKFLSHARRQPKKAFIIYEGD--VYTYEDVDKRSNRVAHALLNHSDLKRGDVVA 109

  Fly    90 LMARNS---THV--GALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDI 149
            |:..|.   .||  |....||:   ..|  :|.||...::....:.:.|:.:.........:::|
  Rat   110 LLMSNEPDFVHVWFGLAKLGCV---VAF--LNSNLRFESLLHCIRTSEPKAMVVGEDLLGSLEEI 169

  Fly   150 GASLGALIIT--VNGKLP-GVISVADIL----QNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTP 207
            ..||...|..  :...:| |::|:.:.|    ..|:|..:....   .:..|...:.:|||||.|
  Rat   170 LPSLPKHIRVWGMKDSVPEGIVSLKEKLSLASDEPVPPSHHVTS---SLKSTCLYIFTSGTTGLP 231

  Fly   208 KAVTLSNSRKL---FEMHSY-LGSDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHF 268
            ||..:|..:.|   |.:.:: ..:||:.|....|...:|.:..:...|......:..:.||.:.|
  Rat   232 KAAVISQFQVLKGSFGLWAFGCTADDIVYITLPLYHSSGALLGIGGCVELGATCVLKKKFSASQF 296

  Fly   269 LDICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAGGHCLVATLKKMQSFLHGSGILR 333
            .:.|.::.|:...........|...|:...:|...::   .|.|:.:.:.:  .:.||...|.::
  Rat   297 WNDCRKYNVTVFQYIGELCRYLCKQPQREGEKDHRVR---LAVGNGMSSDV--WRQFLDRFGNIK 356

  Fly   334 --NAYGLTEVGTLVSYNYDTQSKPTSVGRLMANIRVKIVDSSGQL-------------------- 376
              ..||.|| |.:...|:  ..|..||||:  |....::.|...:
  Rat   357 MCEFYGATE-GNICFMNH--TGKIGSVGRV--NFFYNLLFSFELIKYDFQKDEPLRNEQGWCYCV 416

  Fly   377 -QGPKGLGEILCHNGQPWSGYVGNPLATAE------MRDSAGWYHTGDVGYFDEDHYLHIVERKK 434
             :|..||.....:...|:.||.|:...|..      .:....:::|||:.:.|.:::|:..:|..
  Rat   417 RKGEPGLLVSRVNKKNPFFGYTGSYKQTKSKLLFDVFKKGDVYFNTGDLMFQDHENFLYFWDRIG 481

  Fly   435 DMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSGSKLD-PKHVEQYV 497
            |..::.|......||..|:.::..:.|..|:|: ....||.|...|::|:....|| .|..:|.|
  Rat   482 DTFRWKGENVATTEVANVLGRLDFIQEANVYGVPVPGYEGKAGMTSIILKPNKSLDLEKMYDQVV 546

Fly 498 497
Rat 547 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	113/520 (22%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	105/494 (21%)
Slc27a6	NP_001099615.1	PRK08279	58..612	CDD:236217	109/509 (21%)
Slc27a6	NP_001099615.1	AFD_class_I	77..609	CDD:302604	104/490 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840