DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11391 and Slc27a1

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_006509734.1	Gene:	Slc27a1 / 26457	MGIID:	1347098	Length:	657	Species:	Mus musculus

Alignment Length:	552	Identity:	125/552 - (22%)
Similarity:	220/552 - (39%)	Gaps:	92/552 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 IFRQL-QRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTHVGAL 101
            ||:.: :|||:|:..:..:.....|..|:...:..:....|..|| ...|:|.:..........|
Mouse    92 IFQAVARRQPERLALVDASSGICWTFAQLDTYSNAVANLFRQLGF-APGDVVAVFLEGRPEFVGL 155

  Fly   102 AYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALIITVNGKL-- 164
            ..|....|.....:|.||..          .|...|..|: ..|....|..:.|.:..|:.:|
Mouse   156 WLGLAKAGVVAALLNVNLRR----------EPLAFCLGTS-AAKALIYGGEMAAAVAEVSEQLGK 209

  Fly   165 ------PGVISVADILQNPLPDD--YEPAQFQ-----------RGVDRTMAILCSSGTTGTPKAV 210
                  .|.:....|    |||.  .:|...:           :|:|..:..:.:|||||.|||.
Mouse   210 SLLKFCSGDLGPESI----LPDTQLLDPMLAEAPTTPLAQAPGKGMDDRLFYIYTSGTTGLPKAA 270

  Fly   211 TLSNSR----KLFEMHSY-LGSDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHFLD 270
            .:.:||    ..|..||| :.:.||.|....|....|.|..|...|...:.::..:.||.:.|.|
Mouse   271 IVVHSRYYRIAAFGHHSYSMRAADVLYDCLPLYHSAGNIMGVGQCVIYGLTVVLRKKFSASRFWD 335

  Fly   271 ICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLK---HLLFAGGHCLVATLKKMQSFLHGSGI- 331
            .|    |.:......::..:  |.....|.:|.::   .:..|.|:.|...:  .:.|....|:
Mouse   336 DC----VKYNCTVVQYIGEI--CRYLLRQPVRDVEQRHRVRLAVGNGLRPAI--WEEFTQRFGVP 392

  Fly   332 -LRNAYGLTEVGTLVSYNYDTQSKPTSVG---RLMANI-RVKIV----DSSGQLQGPKGLGEILC 387
             :...||.||....:: |.|  .|..|.|   |::.:: .:::|    |:...|:..:||. |.|
Mouse   393 QIGEFYGATECNCSIA-NMD--GKVGSCGFNSRILTHVYPIRLVKVNEDTMEPLRDSEGLC-IPC 453

  Fly   388 HNGQP---------------WSGYVGN-----PLATAEMRDSAGWYHTGDVGYFDEDHYLHIVER 432
            ..|:|               :.|||.:     .:|.:..|.....|.:|||...||..|::..:|
Mouse   454 QPGEPGLLVGQINQQDPLRRFDGYVSDSATNKKIAHSVFRKGDSAYLSGDVLVMDELGYMYFRDR 518

  Fly   433 KKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSGSKLDPKHVEQY 496
            ..|..::.|......|||.|::::....:|.|:|: ....||.|..|::. ...|:|||..:.|.
Mouse   519 SGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYGVAVPGVEGKAGMAAIA-DPHSQLDPNSMYQE 582

  Fly   497 VRKNVSVQFKHLHGGVQFVPQLAKSANGKVNR 528
            ::|.::...:.:.  ::.:||:..:...|:.:
Mouse   583 LQKVLASYARPIF--LRLLPQVDTTGTFKIQK 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	125/552 (23%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	119/535 (22%)
Slc27a1	XP_006509734.1	AFD_class_I	115..622	CDD:418409	119/529 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839078
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840