DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and Acsm3

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_006230168.1	Gene:	Acsm3 / 24763	RGDID:	62086	Length:	581	Species:	Rattus norvegicus

Alignment Length:	488	Identity:	124/488 - (25%)
Similarity:	189/488 - (38%)	Gaps:	107/488 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 CLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTAD-YEKIKDIGASL-----GALIITVN-- 161
            ||..||........|....|  ||::...:..|..|.| .....||.|:.     ..||::.:
  Rat   134 CLRTGTVLIPGTTQLTQKDI--LYRLQSSKSKCIITDDTLAPAVDIVAAKCENLHSKLIVSQHSR 196

  Fly   162 ---GKLPGVISVA-------DILQNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAVTLSNSR 216
               |.|..::..|       |...|.|                |||..:|||||.||.:.
  Rat   197 EGWGNLKEMMKYASDSHTCVDTKHNEL----------------MAIYFTSGTTGPPKMIG----- 240

  Fly   217 KLFEMHSYLG--------------SDDVQYAPSTLDWLTGLITLV------TAAVFGTVRLISSE 261
               ..||..|              :.||.:..|...|.....:.|      .|.||
  Rat   241 ---HTHSSFGLGLSVNGRFWLDLIASDVMWNTSDTGWAKSAWSSVFSPWTQGACVF--------- 293

  Fly   262 MFSTAHFLDICEQHEVSWTI---------MANSHVAMLANCPKTSAQKLRSLKHLLFAGGHCLVA 317
                ||:|...:...:..|:         .|.:...||.....|.:.|..||||.:.||.   ..
  Rat   294 ----AHYLPRFDSTSILQTLSKFPITVFCSAPTAYRMLIQNDITRSYKFNSLKHCVSAGE---PI 351

  Fly   318 TLKKMQSFLHGSGI-LRNAYGLTEVGTLVSYNY-DTQSKPTSVGRLMANIRVKIVDSSGQLQGPK 380
            ..:.|:.:...:|: :...||.||. .|:..|: ..:.||.|:|:......|:|:|.:|.:..|.
  Rat   352 NPEVMEQWKKKTGLDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFNVEILDENGTILPPG 415

  Fly   381 GLGEILCH--NGQP---WSGYVGNPLATAE-MRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKY 439
            ..|:|...  ..:|   ::.||.||..||. :|  ..:|.|||.||.|||.|...|.|..|::..
  Rat   416 QEGDIAVQVLPDRPFGLFTHYVDNPSKTASTLR--GNFYITGDRGYMDEDGYFWFVARSDDVILS 478

  Fly   440 LGMMYYPHEVEEVIAQMPDVAEVCVFGIFRETEGDAAAASVVLRSGSKLD-----PKHVEQYVRK 499
            .|....|.|||..:.:.|.:||..|........|:...|.:||....||.     .|.::::|:|
  Rat   479 SGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKLHDQEQLKKEIQEHVKK 543

  Fly   500 NVSVQFKHLHGGVQFVPQLAKSANGKVNRQAVK 532
             .:..:|:.. .::|:.:|.|:.:|||.|..::
  Rat   544 -TTAPYKYPR-KIEFIEELPKTVSGKVKRNELR 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	124/488 (25%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	122/481 (25%)
Acsm3	XP_006230168.1	Acs	45..575	CDD:223442	124/488 (25%)
Acsm3	XP_006230168.1	AFD_class_I	48..578	CDD:302604	124/488 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010