Protein Alignment Acsx2 and Acsm2

DIOPT Version :10

• Sequence 1: NP_650830.1
• Gene: Acsx2 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001171448.1
• Gene: Acsm2 / 233799
• MGIID: 2385289
• Length: 600
• Species: Mus musculus
• Alignment Length: 479
• Identity: 113/479 - (23%)
• Similarity: 198/479 - (41%)
• Gaps: 86/479 - (17%)

  Fly   104 GCLFNGTPFHAVNPNLEHNTISSLYKITRPR---ILCCDTADYE-----------KIKDIGASLG 154
            ||:..|..|  :...::..:...||::...:   |:..|....|           |||
Mouse   150 GCMRTGLVF--MPGTIQMRSSDILYRLQASKARAIVAGDEVAQEVDAVAPDCSFLKIK------- 205

  Fly   155 ALIITVNGKLPGVISVADILQNPLPDDYEPAQFQRGVD----RTMAILCSSGTTGTPKAVTLSNS 215
             |:::.|.: .|.::...:|:       |.:...:.|:    .:.||..:|||:|.||....|:.
Mouse   206 -LLVSENSR-EGWLNFKALLK-------EASTIHQCVETESRESAAIYFTSGTSGPPKMAEHSHC 261

  Fly   216 ----RKLFEMHSYLG--SDDVQYAPSTLDWLTGLI------TLVTAAVFGTVRLISSEMFSTAHF 268
                :...:..|:.|  :.|:.:..|...|:..::      .::.|.:|  |.|:..  |.:...
Mouse   262 SLGIKAKMDAASWTGLSTSDIIWTISDTAWIMNILGAFLEPWVLGACIF--VHLLPK--FDSQTV 322

  Fly   269 LDICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLK----HLLFAGGHCLVATLKKMQSFLHGS 329
            |.:...:.::..:.|.....||..      |.|.|.|    |..|:||..|:.  :.::::...:
Mouse   323 LKVLSSYPINTLVGAPIIYRMLLQ------QDLSSYKFPHLHSCFSGGETLLP--ETLENWKAKT 379

  Fly   330 GI-LRNAYGLTEVGTLVSYNYDTQSKPTSVGRLMANIRVKIVDSSGQLQGPKGLGEILCHNGQPW 393
            |: :|..||.||.|.:...:...:.||..:|...|:..|:::|..|.:..|...|:|.......|
Mouse   380 GLEIREIYGQTETGLICRVSRTMKVKPGYLGTAFAHYDVQVIDEQGNVLPPGKEGDIAIRVKPIW 444

  Fly   394 -----SGYVGNPLATAEMRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVI 453
                 ||||.||..|.:......|. .||.|..|.:.|.|.:.|..|::...|....|.|||..:
Mouse   445 PIGMFSGYVDNPKKTQDNIRGDFWL-MGDRGIKDPEGYFHFIGRSDDIINSSGYRIGPSEVENAL 508

  Fly   454 AQMPDVAEVCVFGIFRETEGDAAAASVVLRSG---------SKLDPKHVEQYVRKNVSVQFKHLH 509
            .:.|.|:|..|......:.|:...|.|||...         :|:..:||     |:|:..:|:..
Mouse   509 MEHPAVSETAVISSPDPSRGEVVKAFVVLAPEFLSHDRDQLTKVLQEHV-----KSVTAPYKYPR 568

  Fly   510 GGVQFVPQLAKSANGKVNRQAVKA 533
             .|:||..|.|:..||:.|..::|
Mouse   569 -KVEFVLDLPKTVTGKIERAKLRA 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx2	NP_650830.1	Firefly_Luc_like	51..527	CDD:341237	111/471 (24%)
Acsm2	NP_001171448.1	Adenylate forming domain, Class I superfamily	66..594	CDD:473059	113/479 (24%)