Protein Alignment Acsx2 and ACSL6

DIOPT Version :10

• Sequence 1: NP_650830.1
• Gene: Acsx2 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 136/611 - (22%)
• Similarity: 219/611 - (35%)
• Gaps: 194/611 - (31%)

  Fly    20 SGCSRHSL-----------YNEELTVGQIIFRQLQ----------RQPQRIFQISHTDNTRLTRF 63
            ||.:|.|:           |::..|:.|:..|.|.          |:|::.:|       .|:..
Human    92 SGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQ-------WLSYQ 149

  Fly    64 QMLQNAAKIGCYLRDQGFKKETD-LVGLMARN-----------------------STHVGALAYG 104
            ::...|..:|..|.....|..|| .:|:.|:|                       :...||:.|
Human   150 EVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRY- 213

  Fly   105 CLFNGTPFHAVNPNLEHNTISSLYKITRPR------ILCCDTADYEKIKDIGASLGALIITVNGK 163
             :.|......|..:.....:..|..:.|..      |:..|..: |.:|:.|...|.:|.::.
Human   214 -IINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFE-EALKERGQKCGVVIKSMQ-- 274

  Fly   164 LPGVISVADILQN-------PLPDDYEPAQFQRGVDRTMAILC-SSGTTGTPKAVTLSNSRKLFE 220
                 :|.|..|.       |.|||             ::|:| :|||||.||...|::...:.:
Human   275 -----AVEDCGQENHQAPVPPQPDD-------------LSIVCFTSGTTGNPKGAMLTHGNVVAD 321

  Fly   221 MHSYLGSDDVQYAPSTLDWLTGLITL-------VTAAVF----------GTVRLISSEM------ 262
            ...:|...:.|:||:..|.....:.|       |.:.|:          |.:||:|.:|
Human   322 FSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPT 386

  Fly   263 ----------------FSTAH---------FLDICEQHEVSWTIMANSHV----------AMLAN 292
                            ||.|:         |....:|.||...|:.|..:          |.|..
Human   387 IFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGG 451

  Fly   293 CPKTSAQKLRSLKHLLFAGGHCLVATLKKMQSFLHGSGILRNA--------YGLTEVGTLVSYNY 349
            |.:           ::..|......|:         .|.||.|        ||.||  ......:
Human   452 CVR-----------MIVTGAAPASPTV---------LGFLRAALGCQVYEGYGQTE--CTAGCTF 494

  Fly   350 DTQSKPTS--VGRLMANIRVKIVDSSGQLQ--GPKGLGEILCHNGQPWSGYVGNPLATAEMRDSA 410
            .|....||  ||..:....:|:||.. :|.  ..||.|||.......:.||:.:|..|.|..||.
Human   495 TTPGDWTSGHVGAPLPCNHIKLVDVE-ELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSD 558

  Fly   411 GWYHTGDVGYFDEDHYLHIVERKKDMLKYL-GMMYYPHEVEEVIAQMPDVAEVCVFGIFRETEGD 474
            ||.||||:|.:.....|.|::|||.:.|.. |....|.::|.:..:...||::.|       .||
Human   559 GWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYV-------HGD 616

  Fly   475 AAAASVVLRSGSKL-DPKHVEQYVRK 499
            :..|.:|   |..: ||:.:..:.:|
Human   617 SLKAFLV---GIVVPDPEVMPSWAQK 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx2	NP_650830.1	Firefly_Luc_like	51..527	CDD:341237	125/559 (22%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	125/562 (22%)