Protein Alignment CG11391 and ACSL4

DIOPT Version :9

• Sequence 1: NP_650830.1
• Gene: CG11391 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: XP_024308119.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 717
• Species: Homo sapiens
• Alignment Length: 669
• Identity: 138/669 - (20%)
• Similarity: 231/669 - (34%)
• Gaps: 219/669 - (32%)

  Fly    30 EELTVGQIIFRQLQRQPQ-RIFQ---------ISHTD-NTRLTRF--------QMLQNAAKIGCY 75
            :.|...:|:..:.:.||. ::|:         :::.: |.|:..|        ...:|...|.|.
Human   100 DSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCE 164

  Fly    76 LRDQG-------FKKETDLVGLMARNSTHVGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRP 133
            .|.:.       ||....||.|            |..|......|.:|.:      .:.|.||..
Human   165 TRAEWMIAAQTCFKYNFPLVTL------------YATLGKEAVVHGLNES------EASYLITSV 211

  Fly   134 RILCCDTADYEKIKDIGASLGAL--IITVNGK------------LPGVISVADILQNPLPDDYEP 184
            .:|      ..|:|.....:..:  ||.|:.|            :..:.||.::..||......|
Human   212 ELL------ESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPP 270

  Fly   185 AQFQRGVDRTMAI-LCSSGTTGTPKAVTLSNSRKLFEMHSY------LGSDD--VQYAPSTLDWL 240
            :   |.....||| :.:||:||.||.|.:.:|..:..|...      ||..|  :.|.|  |..:
Human   271 S---RPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLP--LAHV 330

  Fly   241 TGLITLVTAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTIMANSHVAMLANCPK---------- 295
            ..|...::...:|.....||.:..:.....|.:..:...|::..:   ::|..|:
Human   331 LELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPT---LMAAVPEIMDRIYKNVM 392

  Fly   296 TSAQKLRSLKHLLFAGGH---------------CLVATLKKMQSFLHG------SG--------- 330
            :..|::..::..||..|:               |.:...||:::.|.|      ||
Human   393 SKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTH 457

  Fly   331 ---------ILRNAYGLTE---VGTLVSYNYDTQSKPTSVGRLMA-----NIRVKIVDSSGQL-- 376
                     .:...|||||   .||:      |:....:.||:.|     .|::|.....|..
Human   458 RFMNVCFCCPIGQGYGLTESCGAGTV------TEVTDYTTGRVGAPLICCEIKLKDWQEGGYTIN 516

  Fly   377 QGPKGLGEILCHNGQPWS-GYVGNPLATAE--MRDSAG--WYHTGDVGYFDEDHYLHIVERKKDM 436
            ..|...|||:. .||..| ||..|...|||  ..|..|  |:.|||:|.|..|..|.|::||||:
Human   517 DKPNPRGEIVI-GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDL 580

  Fly   437 LKYLGMMYYP-HEVEEVIAQMPDVAEVCVFGIFRETEGDAAAASVVLRSGSKLDPKHVEQYV--- 497
            :|.....|.. .:||..:...|.:..:|.|                    :|.|..:|..:|
Human   581 VKLQAGEYVSLGKVEAALKNCPLIDNICAF--------------------AKSDQSYVISFVVPN 625

  Fly   498 --RKNVSVQFKHLHG-----------GVQFVPQLAKSANG------------------------- 524
              |..:..|.|.:.|           ..:.:.::.::||.
Human   626 QKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGL 690

  Fly   525 -----KVNRQAVKAAYLRD 538
                 |:.|:.::..||:|
Human   691 VTDAFKLKRKELRNHYLKD 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	138/669 (21%)
		AFD_class_I	51..527	CDD:302604	129/634 (20%)
ACSL4	XP_024308119.1	LC-FACS_euk	127..714	CDD:213293	133/642 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148971
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930