DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11391 and Acsl6

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_030101662.1	Gene:	Acsl6 / 216739	MGIID:	894291	Length:	748	Species:	Mus musculus

Alignment Length:	686	Identity:	151/686 - (22%)
Similarity:	241/686 - (35%)	Gaps:	238/686 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QKVWSGCSR---HSLYNEELTVGQIIFRQLQ----------RQPQRIFQ-ISHTDNTRLTRF--- 63
            :.|..||::   | .|::..|:.|:..|.|.          |:|::.:| :|:.:..:...|
Mouse    97 RSVIGGCTQLLTH-YYDDARTMYQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAKRAEFLGS 160

  Fly    64 QMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTH--VGALA-----------YGCLFNGTPFHAV 115
            .:||:..|:|          ....||:.|:|...  :..||           |..|..|:..:.:
Mouse   161 GLLQHDCKVG----------TEQFVGVFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSISYII 215

  Fly   116 N-----------PN-----LEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALI------I 158
            |           |:     |||                     .|:.:..|..|..|:      :
Mouse   216 NTADICTVIVDKPHKATLLLEH---------------------VERKETPGLKLVILMEPFEDAL 259

  Fly   159 TVNGKLPGV-ISVADILQN-----------PLPDDYEPAQFQRGVDRTMAILC-SSGTTGTPKAV 210
            ...||..|| |.....:::           |.|||             ::|:| :|||||.||..
Mouse   260 RERGKKCGVDIKSMQAIEDCGRENHHAPVPPRPDD-------------LSIVCFTSGTTGNPKGA 311

  Fly   211 TLSNSRKLFEMHSYL---------GSDDV-----------------QYAPSTLDWLTGLITL--- 246
            .|::...:.:...:|         ..|||                 |:||:..|.....:.|
Mouse   312 MLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSQWAPTCADVHFSYLPLAHM 376

  Fly   247 ----VTAAVF----------GTVRLISSEM-------FSTAHFL------DICEQHEVS---WTI 281
                |.:.|:          |.:||:|.:|       |.....|      .|..|.:.|   |
Mouse   377 FERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTSLKRW-- 439

  Fly   282 MANSHVAMLANCPKTSAQKLRS--------LKHLLF------AGGHCLVATLKKMQSFLHGSGIL 332
                   :|....|....::||        ...|.|      .|||..:.......:.....|.|
Mouse   440 -------LLEFAAKRKQAEVRSGIIRNNSIWDELFFNKIQASLGGHVRMIVTGAAPASPTVLGFL 497

  Fly   333 RNA--------YGLTEVGTLVSYNYDTQSKPTS--VGRLMANIRVKIVDSSGQLQ--GPKGLGEI 385
            |.|        ||.||  ......:.|....||  ||..:....:|:||:. :|.  ..||.|||
Mouse   498 RAALGCQVYEGYGQTE--CTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAE-ELNYWTCKGEGEI 559

  Fly   386 LCHNGQPWSGYVGNPLATAEMRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYL-GMMYYPHEV 449
            .......:.||:.:...|.|..||.||.||||:|.:..:..|.|::|||.:.|.. |....|.::
Mouse   560 CVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKI 624

  Fly   450 EEVIAQMPDVAEVCVFGIFRETEGDAAAASVVLRSGSKL-DPKHVEQYVRKNVSVQFKHLHGGVQ 513
            |.:..:...||::.|       .||:..|.:|   |..: ||:.:..:.:|      |.:.|..|
Mouse   625 ENIYIRSEPVAQIYV-------HGDSLKAFLV---GIVVPDPEVMPSWAQK------KGIEGTYQ 673

  Fly   514 ---FVPQLAKS----------ANGKVNRQAVKAAYL 536
               ...:|.|:          .:|..:.:.|||.|:
Mouse   674 ELCMKKELKKAILDDMVMLGKESGLHSFEQVKAIYI 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	148/678 (22%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	136/627 (22%)
Acsl6	XP_030101662.1	LC-FACS_euk	141..744	CDD:341250	140/641 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839202
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930