Protein Alignment Acsx2 and ACSF3

DIOPT Version :10

• Sequence 1: NP_650830.1
• Gene: Acsx2 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_777577.2
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 576
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 125/561 - (22%)
• Similarity: 223/561 - (39%)
• Gaps: 119/561 - (21%)

  Fly    35 GQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTHVG 99
            |:..:|:|..:..|:.|    :..||           .||.   .|..:|..:..|.|.::::|.
Human    64 GRHTYRELYSRSLRLSQ----EICRL-----------CGCV---GGDLREERVSFLCANDASYVV 110

  Fly   100 ALAYGCLFNG--TPFHAVNP--NLEHNTISSLYKITRPRILCCD--------TADY-EKIKDIGA 151
            |.....:..|  .|.:..:|  .||:              :.||        :.:| |.:..:..
Human   111 AQWASWMSGGVAVPLYRKHPAAQLEY--------------VICDSQSSVVLASQEYLELLSPVVR 161

  Fly   152 SLGALIITVNGKLPGVI--SVADILQNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAV--TL 212
            .||..::.:.   |.:.  :|.:..:.|:|:       |...::...|:.:|||||.||.|  |.
Human   162 KLGVPLLPLT---PAIYTGAVEEPAEVPVPE-------QGWRNKGAMIIYTSGTTGRPKGVLSTH 216

  Fly   213 SNSRKLFE--MHSYLGS-DDVQYAPSTLDWLTGLI-----------TLVTAAVFGT----VRLIS 259
            .|.|.:..  :|.:..: |||......|..:.|::           |.|....|..    .:.:|
Human   217 QNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLS 281

  Fly   260 SE-------MFSTAHFLDICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAGGHCL-V 316
            ||       |.....:..:.|.::..:| ..::...:.|.|    .:|:|    |:.:|...| :
Human   282 SETPRINVFMAVPTIYTKLMEYYDRHFT-QPHAQDFLRAVC----EEKIR----LMVSGSAALPL 337

  Fly   317 ATLKKMQSFLHGSGILRNAYGLTEVGTLVSYNYDTQSK-PTSVGRLMANIRVKIVD--------- 371
            ..|:|.:: :.|..:|.. ||:||:|..:|....|..: |.|||..:..::|:||.
Human   338 PVLEKWKN-ITGHTLLER-YGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACS 400

  Fly   372 ----SSGQLQGPK---GL----GEILCHNGQPWSGYVGNPLATAEMRDSAGWYHTGDVGYFDEDH 425
                :.|..:|.|   |.    ||:|......:..|...|..|.......||:.|||...|.:..
Human   401 YTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQ 465

  Fly   426 YLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEVCVFGIFRETEGDAAAASVVLRSGSKLDP 490
            |........|::|..|......|||..:...|.:.:|.|.|:...|.|....|.|.||.|..|..
Human   466 YWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH 530

  Fly   491 KHVEQYVRKNVSVQFKHLHGGVQFVPQLAKSANGKVNRQAV 531
            :.::::.| ||...:. :...:..|.::.::..||::::|:
Human   531 RELKEWAR-NVLAPYA-VPSELVLVEEIPRNQMGKIDKKAL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx2	NP_650830.1	Firefly_Luc_like	51..527	CDD:341237	120/539 (22%)
ACSF3	NP_777577.2	MCS	55..571	CDD:341264	125/561 (22%)