DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11391 and acs-9

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_510728.2	Gene:	acs-9 / 188659	WormBaseID:	WBGene00020634	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	527	Identity:	135/527 - (25%)
Similarity:	210/527 - (39%)	Gaps:	119/527 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 DNTRLTRFQMLQNAAKIGCYLRDQGFKK-ETDLVGLMARNSTHVGALAYGCLFNGTPFHAVNPNL 119
            ||..:|..::.|..:|:...|.:.|..: :|.||.|  .||.....|...|...|    ||...:
Worm    30 DNQVITFEEIPQLVSKLVYKLLELGISQGDTILVCL--PNSIWYPLLFLSCAKIG----AVLSGI 88

  Fly   120 EHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALIITVNGKL--PGVISVADILQNPLPD-- 180
            .|.:.:...|.:              :|..||.|    :..|.|:  ....::::.....|||
Worm    89 SHESTAGEIKYS--------------LKQSGAKL----VFTNEKVSKENYWALSENSVEVLPDSV 135

  Fly   181 -----------DYEPAQFQRGVDRTMAILCSSGTTGTPKAVTLSN--------SRKLFEMHSYLG 226
                       |:.|....  :|..:....||||||.||...|::        |.|.|.....|
Worm   136 KTYIDRITGHEDFRPENLD--IDSILLAPFSSGTTGAPKCCLLTHRNFLAATYSLKKFLFDQLL- 197

  Fly   227 SDDVQYAPSTLDWL-----TGLITLVTAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTI----- 281
               .|.:..||.:|     :|...|:...:.|....|.|| |.....:|:.|::|:. ||
Worm   198 ---AQSSMKTLAFLPFHHASGFWALLICLLEGCTTYIMSE-FHPIVMMDLIEKYEID-TINIVPP 257

  Fly   282 MANSHVAM---LANCPKTSAQKLRSLKHLLFAGG-----HC--LVATLKKMQSFLHGSGILRNAY 336
            :||..:.|   ...||        ||:.:|....     .|  |::...::..|:.|       |
Worm   258 IANIFLKMGILQGRCP--------SLRTILCGSSGLQKDRCKRLLSIFPQVTHFIQG-------Y 307

  Fly   337 GLTEVGTL--VSYNYDTQSKPTSVGRLMANIRVKIVDSSGQLQGPKGLGEILCHNGQPWSGYV-G 398
            |:||:..|  |:...|......|.|.::.....|:      .:.|.|..|:...:......|. |
Worm   308 GMTELVVLSCVTPFDDNFEHLGSCGHILPGFETKL------FEHPTGETELWLKSDAIMKAYKNG 366

  Fly   399 NPLATAEMRDSAGWYHTGDV-----GYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPD 458
            .|     ..|...|.||||:     |:|      ::|:|.||::|..|....|.|:|.||..:|.
Worm   367 TP-----NLDEDDWLHTGDIVTEKGGFF------YVVDRMKDLIKLNGYQVSPTEIENVILTLPK 420

  Fly   459 VAEVCVFGIFRETEGDAAAASVVLRSGSK--LDPKHVEQYVRKNVSVQFKHLHGGVQFVPQLAKS 521
            ||||.|.||..|..|....|.:||...:.  |..||:|..:::.:|. .|.|.|||..:.::.||
Worm   421 VAEVAVVGIEDELCGQLPKAYIVLEKNADELLFLKHLEHTMKEKLSA-VKQLRGGVSIIKEMPKS 484

  Fly   522 ANGKVNR 528
            ::||:.:
Worm   485 SSGKIQK 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	135/527 (26%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	135/524 (26%)
acs-9	NP_510728.2	CaiC	1..494	CDD:223395	135/527 (26%)
acs-9	NP_510728.2	Firefly_Luc_like	26..490	CDD:213279	135/524 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880