DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11391 and acs-16

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_490859.1	Gene:	acs-16 / 171714	WormBaseID:	WBGene00018579	Length:	569	Species:	Caenorhabditis elegans

Alignment Length:	569	Identity:	112/569 - (19%)
Similarity:	209/569 - (36%)	Gaps:	110/569 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTH 97
            |:.|:|:  .:.:..|:..:..::...||..:::.....:.......|. |:.|.|.:...|.:.
Worm    35 TIPQLIY--TKSEMDRVAAVFDSEKLSLTFSKIVSEMESLAAGFLSIGL-KQGDRVLVAGSNHSQ 96

  Fly    98 VGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPR-------ILCCDTADYEK------IKDI 149
            |...|..|...|..|...|||..::     |.:.|..       |:|.....||.      :.:|
Worm    97 VMLCALACSRAGLVFSLANPNYPNS-----YSLKRALELGEFQCIVCFRAHQYEADHLNNLLLEI 156

  Fly   150 GASL-----------------GALIITVNGKLPGVISVADILQN-------PLPDDYEPAQFQRG 190
            ...|                 ..::...:.|..|..:::::...       .|||      |.:.
Worm   157 APELMRSRKGQLKSELLPKLTHVILAEEDHKHAGTFTLSEVFLKSSKEKIAKLPD------FSKW 215

  Fly   191 VDRTMAIL-CSSGTTGTPKAVTLSNSRKL---FEMHSYLGSDDVQYAPSTLD-WLTGLITLVTAA 250
            ....:|.| .:.||||.||.:.||:.:.|   ..:.:..|.:|.......|. :...:..|:..:
Worm   216 SSHKLACLQFTLGTTGAPKLIALSHYQMLNGARAVAAAFGINDKHVLACALPIFRIAIFNLICLS 280

  Fly   251 VFGT-VRLI-------SSEMFSTAHFLDICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHL 307
            .|.| .|:|       ...:||:.      .::..:..:...:.:.:|....:|...||.:|:::
Worm   281 PFLTECRIIFPDATPLPKNLFSSV------SKYRCTTLLSNGAALRLLLKISQTQRVKLSALENI 339

  Fly   308 LFAGGHCLVATLKKMQSFLHGSGILRNAYGLTEVGTLVSYNYDTQSKPTSVGRLMANIRVKIV-- 370
            |..|.......||.::.......|:...|.|||.|::............:||:.:|.....::
Worm   340 LLIGDRVSKEVLKLIKVQAENVKIIAVGYLLTETGSIPLMGDQNSDFTRNVGKAIAGYEAHLIPL 404

  Fly   371 -DSSGQLQGPKGLGEIL--CHNGQPWSGYVGNPLATAEMRDSAGWYHTGDVGYFDEDHYLHIVER 432
             .|..|::..| ||::|  .:.|..:.||      ..:.:....|..|||:|..||:..:.:|..
Worm   405 DGSENQVETGK-LGKLLIRVYYGSTFMGY------APDTKGKEKWVDTGDIGRMDENGAIEVVAS 462

  Fly   433 KKDMLKYLGMMYYPH-EVEEVIAQ---------------MPDVAEVCVFGIFRETEGDAAAASVV 481
            :.|::.........| .:|.::.|               .| |..|||   .|.|:..||.....
Worm   463 EDDLIYDKNNCLVEHWNLERLLNQNDLIKGVQVVSRGRGQP-VTAVCV---ARSTQFHAAKLKDE 523

  Fly   482 LRSGSKLDPKHVEQYVRKNVSV---QFKHLHGGVQFVPQLAKSANGKVN 527
            |:|..:   .|  .:|..:|..   .|..:|..:|.....|...:|:::
Worm   524 LKSMCR---SH--HFVAPDVFAFVDDFPRVHTKIQKFRIRAMLESGQIS 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	112/569 (20%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	108/549 (20%)
acs-16	NP_490859.1	CaiC	35..565	CDD:223395	111/565 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810