Protein Alignment Acsx2 and Acsl4

DIOPT Version :10

• Sequence 1: NP_650830.1
• Gene: Acsx2 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001418578.1
• Gene: Acsl4 / 113976
• RGDID: 69401
• Length: 711
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 139/669 - (20%)
• Similarity: 230/669 - (34%)
• Gaps: 219/669 - (32%)

  Fly    30 EELTVGQIIFRQLQRQPQ-RIFQ---------ISHTD-NTRLTRF--------QMLQNAAKIGCY 75
            :.|...:|:..:.:.||. ::|:         |::.: |.|:..|        ...:|...|.|.
  Rat    94 DSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCE 158

  Fly    76 LRDQG-------FKKETDLVGLMARNSTHVGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRP 133
            .|.:.       ||....||.|            |..|......|.:|.:      .:.|.||..
  Rat   159 TRAEWMIAAQTCFKYNFPLVTL------------YATLGKEAVVHGLNES------EASYLITSV 205

  Fly   134 RILCCDTADYEKIKDIGASLGAL--IITVNGK------------LPGVISVADILQNPLPDDYEP 184
            .:|      ..|:|.....:..:  ||.|:.|            :..:.||.::...|......|
  Rat   206 ELL------ESKLKAALLDINCVKHIIYVDNKTINRAEYPEGLEIHSMQSVEELGSKPENSSIPP 264

  Fly   185 AQFQRGVDRTMAI-LCSSGTTGTPKAVTLSNSRKLFEMHSY------LGSDD--VQYAPSTLDWL 240
            :   |.....||| :.:||:||.||.|.:.:|..:..|...      ||..|  :.|.|  |..:
  Rat   265 S---RPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLP--LAHV 324

  Fly   241 TGLITLVTAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTIMANSHVAMLANCPK---------- 295
            ..|...::...:|.....||.:..:.....|.:..:...|::..:   ::|..|:
  Rat   325 LELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPT---LMAAVPEIMDRIYKNVM 386

  Fly   296 TSAQKLRSLKHLLFAGGH---------------CLVATLKKMQSFLHG------SG--------- 330
            :..|::..::..||..|:               |.:...||:::.|.|      ||
  Rat   387 SKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTH 451

  Fly   331 ---------ILRNAYGLTE---VGTLVSYNYDTQSKPTSVGRLMA-----NIRVKIVDSSGQL-- 376
                     .:...|||||   .||:      |:....:.||:.|     .|::|.....|..
  Rat   452 RFMNVCFCCPIGQGYGLTESCGAGTV------TEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVH 510

  Fly   377 QGPKGLGEILCHNGQPWS-GYVGNPLATAE--MRDSAG--WYHTGDVGYFDEDHYLHIVERKKDM 436
            ..|...|||:. .||..| ||..|...|||  ..|..|  |:.|||:|.|..|..|.|::||||:
  Rat   511 DKPNPRGEIVI-GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDL 574

  Fly   437 LKYLGMMYYP-HEVEEVIAQMPDVAEVCVFGIFRETEGDAAAASVVLRSGSKLDPKHVEQYVRKN 500
            :|.....|.. .:||..:...|.:..:|.|                    :|.|..:|..:|..|
  Rat   575 VKLQAGEYVSLGKVEAALKNCPLIDNICAF--------------------AKSDQSYVISFVVPN 619

  Fly   501 -----VSVQFKHLHGG-----------VQFVPQLAKSANG------------------------- 524
                 :..|.|.:.|.           .:.:.::.::||.
  Rat   620 QKKLTLLAQQKGVEGSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGL 684

  Fly   525 -----KVNRQAVKAAYLRD 538
                 |:.|:.:|..||:|
  Rat   685 VTDAFKLKRKELKNHYLKD 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx2	NP_650830.1	Firefly_Luc_like	51..527	CDD:341237	129/634 (20%)
Acsl4	NP_001418578.1	LC_FACS_euk1	121..696	CDD:341294	130/633 (21%)