DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and SLC27A3

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_077306.3	Gene:	SLC27A3 / 11000	HGNCID:	10997	Length:	683	Species:	Homo sapiens

Alignment Length:	388	Identity:	102/388 - (26%)
Similarity:	160/388 - (41%)	Gaps:	60/388 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 IKDIGASLGALIITVNGKLPGVISVADILQNPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAV 210
            |.|:.|.:.|   .|:|.:||.:|      :|           :.:..|...:.:|||||.|||.
Human   254 ISDLLAEVSA---EVDGPVPGYLS------SP-----------QSITDTCLYIFTSGTTGLPKAA 298

  Fly   211 TLSNSRKLFEMHSY-----LGSDDVQYAPSTLDWLTG-LITLVTAAVFGTVRLISSEMFSTAHFL 269
            .:|: .|:.:...:     :..:||.|....|..::| |:.:|.....|...::.|: ||...|.
Human   299 RISH-LKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSK-FSAGQFW 361

  Fly   270 DICEQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAGGHCLVATLKKMQSFLHGSGILR- 333
            :.|:||.|:...........|.|.|.:.|:  |..|..|..|......|.::   |:...|.|:
Human   362 EDCQQHRVTVFQYIGELCRYLVNQPPSKAE--RGHKVRLAVGSGLRPDTWER---FVRRFGPLQV 421

  Fly   334 -NAYGLTEVGTLVSYNYDTQSK-------------PTSVGRLMANIRVKIVDSSGQLQ----GPK 380
             ..||||| |.:.:.||..|..             |.|:.|........|.|..|...    |..
Human   422 LETYGLTE-GNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEP 485

  Fly   381 GLGEILCHNGQPWSGYVGNP-LATAEM-----RDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKY 439
            ||.........|:.||.|.| ||..::     |....:::|||:...|:..:|...:|..|..::
Human   486 GLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRW 550

  Fly   440 LGMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSGSKLDPKHVEQYVRKNV 501
            .|......||.||...:..:.||.|:|: ....||.|..|::|||....||...:..:|.:|:
Human   551 KGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSENL 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	102/388 (26%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	102/388 (26%)
SLC27A3	NP_077306.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	119..145
SLC27A3	NP_077306.3	hsFATP2a_ACSVL_like	163..673	CDD:213304	102/388 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840