DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11391 and slc27a3

DIOPT Version :9

Sequence 1:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_002938916.1	Gene:	slc27a3 / 100494612	XenbaseID:	XB-GENE-6459618	Length:	617	Species:	Xenopus tropicalis

Alignment Length:	505	Identity:	110/505 - (21%)
Similarity:	194/505 - (38%)	Gaps:	68/505 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNS-- 95
            ||..|...|:..:|.:.|.:............:..|  :|...|......|:.|.|.|...|.
Frog    51 TVLDIFLHQVSIRPDKNFILFQDQAYTFKEVDLKSN--QIAWALNKHAKVKQGDCVALFLGNEPA 113

  Fly    96 ---THVGALAYGCLFNGTPFHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGALI 157
               ..:|....||     ....:|.|:...:....::.:..::|.........::::..:|....
Frog   114 YIWIWIGLCKLGC-----SMACLNYNIRLKSFLHCFRSSGAKVLIAAPELRNAVEEVLPTLKEQN 173

  Fly   158 ITV-----NGKLPGVISVADILQ----NPLPDDYEPAQFQRGVDRTMAILCSSGTTGTPKAVTLS 213
            :.:     .....||.|:.|.::    ||:|..|   :.:.....|...:.:|||||.|||..::
Frog   174 VQIFYLSRESATDGVDSLLDKVEAASDNPVPKSY---RSEVNAKSTALYIYTSGTTGLPKAAIVN 235

  Fly   214 NSRKLFEMHSYLG------SDDVQYAPSTLDWLTGLITLVTAAVFGTVRLISSEMFSTAHFLDIC 272
            :.|.|  |.|.|.      |.||.|.|..|....|::..|...:......:....||.:.|.|.|
Frog   236 HGRLL--MSSSLSTLAGVTSTDVVYIPLPLYHSAGMMIGVRGCIQKGACCVLRSKFSASQFWDDC 298

  Fly   273 EQHEVSWTIMANSHVAMLANCPKTSAQKLRSLKHLLFAGGHCLVATLKKMQSFLHGSGILR--NA 335
            .::.|:...........|.|.||....|...::   .|.|:.:...:.|  .|:|..|.::  ..
Frog   299 RKYNVTVVQYIGEIFRYLCNTPKKDNDKNHRVR---LALGNGIRPDVWK--EFVHRFGNIKIFEF 358

  Fly   336 YGLTEVGTLVSYNYDTQSKPTSVGR---LMANIR----VK--------IVDSSGQL----QGPKG 381
            |..|| ...|.:||  ..|..::||   |...:|    ||        :.|:||..    .|..|
Frog   359 YAATE-SNAVFFNY--TGKVGAMGRSSFLQKLLRPYGLVKYDVEKDEIVRDASGHCISVKTGETG 420

  Fly   382 LGEILCHNGQPWSGYVGNPLATAE------MRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYL 440
            |.....:...|::||.|:...|.:      .::...:::|||:...|::.:::..:|..|..::.
Frog   421 LLIAKINTVAPFTGYAGDKAQTEKKKLQNVFKNGDLYFNTGDLVMTDKEGFIYFQDRVGDTFRWK 485

  Fly   441 GMMYYPHEVEEVIAQMPDVAEVCVFGI-FRETEGDAAAASVVLRSGSKLD 489
            |......||.:::.....:.|..|:|: ....||.....|:.|:.|.:.|
Frog   486 GENVATTEVADIVGMADFIEEANVYGVSVPYHEGRIGMVSIKLKEGKEFD 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	110/505 (22%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	104/487 (21%)
slc27a3	XP_002938916.1	AFD_class_I	71..607	CDD:388389	104/485 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910