DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11659 and ACOS5

DIOPT Version :9

Sequence 1:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_176482.1	Gene:	ACOS5 / 842596	AraportID:	AT1G62940	Length:	542	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	148/569 - (26%)
Similarity:	264/569 - (46%)	Gaps:	75/569 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DND---QKIWSGEPVVKYFDPD-LSIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLA 70
            ||:   :.::...|:     || |::.|.:...:..:.:..|.:.|..|..:|.|:::.:..|||
plant     8 DNEYIFRSLYPSVPI-----PDKLTLPEFVLQGVEEYTENVAFVEAVTGKAVTYGDVVRDTKRLA 67

  Fly    71 SYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCD 135
            ..:.||||.:..::.::..|......:|......|..|...|.|.....|:|..:.:....|..|
plant    68 KALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITD 132

  Fly   136 GDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLEKG-------NDQTLAI 193
            ...:|||:|    |.:.::.     |...||:..|      |::.. ||.|       |::.|..
plant   133 ATNYEKVKS----LGLPVIV-----LGEEKIEGAV------NWKDL-LEAGDKCGDTDNEEILQT 181

  Fly   194 -LC----SSGTTGTPKAVTITNSRHILAG-------------NYHLTTADVQYSHNTLDWITGLL 240
             ||    ||||||..|.|.:|: |:::|.             ...:|...:.:.|     |.|::
plant   182 DLCALPFSSGTTGLQKGVMLTH-RNLIANLCSTLFGVRSEMIGQIVTLGLIPFFH-----IYGIV 240

  Fly   241 TTITSGVFSTTRIIADNAFDPAFALRIIEEYKVTWT-IQPPSSMALMINCPDFETCDLSSLR--C 302
            ....:.:.:..:::|.:.:|....|..:..::|::. |.||..:.|:.| |..:..|||.|:  .
plant   241 GICCATMKNKGKVVAMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKN-PIVDEFDLSKLKLQS 304

  Fly   303 YMFGGSRAALEVQKGIRSRLSHNCLQFVYGFTELGAMATINCHFDEKTG-------SVGQLVNGL 360
            .|...:..|.|:.....::..:..:|..||.||...:..  .|.|.:.|       |||.::..|
plant   305 VMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITL--THGDPEKGQGIAKRNSVGFILPNL 367

  Fly   361 KMK-IKNDDGESLGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYI 424
            ::| |..|.|.||..:..||:|:.:.....||:.|:.||....|..||.|:||:||:|.||.::|
plant   368 EVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFMNKEETDKTIDEQGWLHTGDIGYIDDDGDIFI 432

  Fly   425 MDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVV 489
            :||.||::||:.....|.::|:::...|.|.:|.|..:.....|:..||.||....:..:.:|::
plant   433 VDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVINPKATEKEEDIL 497

  Fly   490 DYVRSRTDSKYKQLNGGAV-IVDDLQRSANGKTNRMANKAHFLHLKNRK 537
            ::|.:.. :.||::.  || .||.:.:|.:||..|...:...|.: |:|
plant   498 NFVAANV-AHYKKVR--AVHFVDSIPKSLSGKIMRRLLRDKILSI-NKK 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	141/534 (26%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	137/511 (27%)
ACOS5	NP_176482.1	PLN02330	1..542	CDD:215189	147/567 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920