Protein Alignment Acsx1R and ACSBG2

DIOPT Version :10

• Sequence 1: NP_650829.1
• Gene: Acsx1R / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 697
• Identity: 142/697 - (20%)
• Similarity: 254/697 - (36%)
• Gaps: 199/697 - (28%)

  Fly     2 PYTPENSYDND---------QKIWS----GEPVVKY------FDPDLSIGEIIFHEMRR---HPQ 44
            |.|.|.:.|.:         .::|:    ||.:::.      .:..::|.|.....:.|   :|.
Human     5 PKTQEGAKDLEVDMNKTEVTPRLWTTCRDGEVLLRLSKHGPGHETPMTIPEFFRESVNRFGTYPA 69

  Fly    45 LTAQISATEGTVLTRGELLANAMRLASYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAFH 109
            |.:: :..:..:|...:......:.|..:..|||.:...||::|.|:......|......|....
Human    70 LASK-NGKKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCV 133

  Fly   110 SLNITYDRDTIEKIYKVTRPSIIFCDGD-EFEKVRS--------ATAELDVKIVTMRNHPL---- 161
            .:..|...:..:.:....:.:|:..:.| :.:|:.|        ..|.:..::...:|:.|
Human   134 GIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYRLPMKKNNNLYSWD 198

  Fly   162 DSIKIDEVVA-TPIEENFQPAKLEKGNDQTLAILCSSGTTGTPKAVTITNSRHILAGNYHLTTAD 225
            |.:::...:. |.:|   |..:.:|.| |...::.:|||||.||.|.:
Human   199 DFMELGRSIPDTQLE---QVIESQKAN-QCAVLIYTSGTTGIPKGVML----------------- 242

  Fly   226 VQYSHNTLDWITGLLT----------TITS------------GVFSTTRIIADNAFDPAFALR-- 266
               ||:.:.||.|.:|          |:.|            .::...:|.|...|..|.||:
Human   243 ---SHDNITWIAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGT 304

  Fly   267 ---IIEEYKVTWTIQPP---------------SSMAL----------------------MINCP- 290
               .::|.|.|..|..|               .||.|                      ..|.|
Human   305 LVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPV 369

  Fly   291 ---DFETCDLSSLR-------CYMFGGSRAALEVQKGIRSRLSHNC-LQFVYGFTELGAMATINC 344
               ..:|...|.::       |:.|....|.|. |:.....||.:. :..:||.:|.....||:.
Human   370 SYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLN-QETAEFFLSLDIPIGELYGLSESSGPHTISN 433

  Fly   345 HFDEKTGSVGQLVNGLKMKI--KNDDGESLGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGW 407
            ..:.:..|.|:::.|.|..:  :|.||       |||:|:.....:.||..:|.||....|..||
Human   434 QNNYRLLSCGKILTGCKNMLFQQNKDG-------IGEICLWGRHIFMGYLESETETTEAIDDEGW 491

  Fly   408 YHSGDLGYMDRDGFLYIMDRKKEML---KYQNIMYYPNDIESVI-SEMPQVAEVCVFG------- 461
            .||||||.:|..||||:....||:|   ..:|:.  |..:|::: .::|.::...:.|
Human   492 LHSGDLGQLDGLGFLYVTGHIKEILITAGGENVP--PIPVETLVKKKIPIISNAMLVGDKLKFLS 554

  Fly   462 -------IWSNIFGDE------AAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVDDL 513
                   ..:.:.|:.      .|....:.|||  :|..|.:.|:.:....||.:..|   ::.:
Human   555 MLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGS--QASTVTEIVKQQDPLVYKAIQQG---INAV 614

  Fly   514 QRSANGKTNR---------------------MANKAHFLHLKNRKNI 539
            .:.|.....|                     |..|.||:..|.:|.|
Human   615 NQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQI 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1R	NP_650829.1	Firefly_Luc_like	47..522	CDD:341237	122/590 (21%)
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	130/629 (21%)