Protein Alignment Acsx1R and ACSF2

DIOPT Version :10

• Sequence 1: NP_650829.1
• Gene: Acsx1R / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001275897.1
• Gene: ACSF2 / 80221
• HGNCID: 26101
• Length: 640
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 132/544 - (24%)
• Similarity: 234/544 - (43%)
• Gaps: 64/544 - (11%)

  Fly    30 SIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLASYMRSLGLLQSDIVGLIGRNTTHM 94
            ::|:.:....:|.|:..|.:...|...||..:|.....:.||.:.|:||.:.|.:|:.|.|:...
Human    98 TVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAW 162

  Fly    95 LAVAYACFFNGIAFHSLNITYDRDTIEKIY-KVTRPSIIF----------------CDGDEFEKV 142
            :.:..|....||...|:|..|....:|.:. ||...:::|                |  .|.|..
Human   163 VLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQIC--PEVENA 225

  Fly   143 RSATAEL----DVKIVTMRNHPL-DSIKIDEVVATPIEENFQPAKLEKGNDQTLA------ILCS 196
            :....:.    |:..|...:.|| .::.:|||||.  ....|.....:.|.|.|:      |..:
Human   226 QPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAA--GSTRQHLDQLQYNQQFLSCHDPINIQFT 288

  Fly   197 SGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNTLDWITGLLT------------TITSGVFS 249
            |||||:||..|:  |.:.:..|.::....::....|.:.:..:|.            |:...::.
Human   289 SGTTGSPKGATL--SHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYG 351

  Fly   250 TTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDLSSLRCYMFGGSRAALEV 314
            .|.|:|...|:...||..|...:.|:....|:....::|.|||.:.|:|::...:..||.|..|:
Human   352 ATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPEL 416

  Fly   315 QKGIRSRLSHNCLQFVYGFTELGAMATINCHF-----DEKTGSVGQLVNGLKMKIKNDDGESLGP 374
            .:.|.::::...|...||.||...:..  .||     ::|..|||:::...:.:|.|.:..:|..
Human   417 IRAIINKINMKDLVVAYGTTENSPVTF--AHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAK 479

  Fly   375 -DEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIM 438
             :..||:||.......||:|...:|....|...||.:||:..|:..||..|:.|.|:|:......
Human   480 LNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGEN 544

  Fly   439 YYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTD----SK 499
            .||.::|......|:|.||.|.|:..:..|:|..|.:..|.|.|...:::..:.:.:..    .|
Human   545 IYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPK 609

  Fly   500 YKQLNGGAVIVDDLQRSANGKTNR 523
            |      .|.|.:...:.:||..:
Human   610 Y------IVFVTNYPLTISGKIQK 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1R	NP_650829.1	Firefly_Luc_like	47..522	CDD:341237	129/524 (25%)
ACSF2	NP_001275897.1	PRK08315	82..640	CDD:236236	132/544 (24%)