DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11659 and acsl3a

DIOPT Version :9

Sequence 1:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_001038593.1	Gene:	acsl3a / 567157	ZFINID:	ZDB-GENE-050420-181	Length:	713	Species:	Danio rerio

Alignment Length:	687	Identity:	142/687 - (20%)
Similarity:	232/687 - (33%)	Gaps:	210/687 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SGEPVVKYFDPDLSIGEIIFHEMRRHPQL---------------------TAQISATEGTVLTRG 60
            ||:|...|.|    :..:...||..||.:                     |.::.:.|......|
Zfish    54 SGDPAGPYRD----VAALKGLEMCLHPGINTLDQVFQSSVSHFPNSDCLGTRELLSEEDETQEDG 114

  Fly    61 ELLANAM----RLASY-------------MRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAF 108
            ::....:    |..||             :.:||......:.:........:..|.|||......
Zfish   115 KVFKKVILGEYRWMSYEQVFKEVNAFGSGLAALGQKPMKNIAIFCETRAEWIIAAQACFMYNFPL 179

  Fly   109 HSLNITYDRDTIEKIYKVTRPSIIFCDGDEFE-KVRSATAE---------LDVKIVTMRNHP--- 160
            .:|..|.....|.........|.|....|..| |::|...|         :|.|:.|...:|
Zfish   180 VTLYSTLGGPAIAHGLNEAEVSHIITSKDLLETKLKSIFIEVPRLCHVIVVDDKLSTSSEYPRGI 244

  Fly   161 ----LDSIKIDEVVATPIEENFQPAKLEKGNDQTLAILCSSGTTGTPKAVTITNSRHI--LAGNY 219
                :.|:|  |:.|.|  ||....|....:.....|:.:||:||.||.|.|::|..|  :.|..
Zfish   245 SIHSMASVK--ELGARP--ENASKPKNPPCSSDVAVIMYTSGSTGVPKGVMISHSNIISGITGMT 305

  Fly   220 H----LTTADVQYSHNTLDWITGL---LTTITSGV---FSTTRIIADN----------------- 257
            |    |...|....:..|..:..|   :..:..|.   :|:.:.::|.
Zfish   306 HRIPKLVEDDTYIGYLPLAHVLELSAEMVCLAHGCRIGYSSPQTLSDQSTKIKKGSRGDISVLRP 370

  Fly   258 ---AFDPAFALRI-------IEE--------------YKVTWTIQPPSSMALMINCPDFETCDL- 297
               |..|....||       :|:              ||:       ..:|:..:.|   .||.
Zfish   371 TLMAAVPEIMDRIYKNVMLRVEQMSGFQRTLFLLAYNYKM-------EQLAMGYSTP---LCDKL 425

  Fly   298 ----------SSLRCYMFGGSRAALEVQKGIRSRLSHNCLQFV------YGFTELGAMATINCHF 346
                      ..||..:.||:..:...|     |..:.|  |.      ||.||.....||:..:
Zfish   426 VFRKVRALLGGRLRVLLSGGAPLSAATQ-----RFMNIC--FCCPVGQGYGLTETCGAGTISHLW 483

  Fly   347 DEKTGSVGQLVNGLKMKIKN--DDG--ESLGPDEIGEVCIMNNQHWSGYYGNEVETRN--MRDSL 405
            |..||.||..:...::::|:  :.|  .:..|...||:.:.......|||.|..:|..  ..|..
Zfish   484 DYSTGRVGAPLVCCELQLKDWIEGGYHSTDLPCPRGEILVGGPSITMGYYKNTHKTSEDFFVDKK 548

  Fly   406 G--WYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYP-NDIESVISEMPQVAEVCVF------- 460
            |  |:.:||:|.:..||.|.|:||||:::|.|...|.. ..:|:.:...|.|..:|.:
Zfish   549 GQRWFCTGDIGEIHGDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLVDNICAYANSDESY 613

  Fly   461 ----------------------GIWSNIFG----DEAAAAVVKK--LGSELEAQDVVDYVRSR-- 495
                                  |:|..:..    :||...|:.:  |.::||..::...:|..
Zfish   614 VIGFVVPNQKQLLALAERKRVRGLWEELCNNPVIEEAVLTVLTEAALTAQLERFEIPRKIRLSVE 678

  Fly   496 ---------TDS---KYKQLNGGAVIVDDLQRSANGK 520
                     |||   |.|:|.  ....:|::|....|
Zfish   679 PWTPDTGLVTDSFKLKRKELK--THYQNDIERMYGAK 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	138/678 (20%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	132/636 (21%)
acsl3a	NP_001038593.1	PLN02387	77..710	CDD:215217	132/655 (20%)
acsl3a	NP_001038593.1	LC-FACS_euk	123..710	CDD:213293	129/609 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930