Protein Alignment Acsx1R and SLC27A1

DIOPT Version :10

• Sequence 1: NP_650829.1
• Gene: Acsx1R / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 117/535 - (21%)
• Similarity: 185/535 - (34%)
• Gaps: 150/535 - (28%)

  Fly    39 MRRHPQLTAQISATEGTVLTRGELLANAMRLASYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFF 103
            ::|.|:..|.:.|..|...|..:|.|.:..:|:..|.||....|:|.:........:.:......
Human    86 VQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAK 150

  Fly   104 NGIAFHSLNITYDRDTI----------------EKIYKVTRPS-------IIFCDGDEFEKVRSA 145
            .|:....||:...|:.:                |.:..|...|       |.||.||
Human   151 AGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGD-------- 207

  Fly   146 TAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKL-EKGNDQTLAILCSSGTTGTPKAVTIT 209
               |..:.:....|.||.: :.|....|:      |:: .||.|..|..:.:|||||.|||..:.
Human   208 ---LGPEGILPDTHLLDPL-LKEASTAPL------AQIPSKGMDDRLFYIYTSGTTGLPKAAIVV 262

  Fly   210 NSRH--ILAGNYH---LTTADVQYS----HNTLDWITGL-------LTTITSGVFSTTRIIADNA 258
            :||:  :.|..:|   :..|||.|.    :::...|.|:       ||.:....||.:|...|
Human   263 HSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDD-- 325

  Fly   259 FDPAFALRIIEEYKVTWTIQPPSSMALMINCP--DFETCDLSSLRCYMFG--------------- 306
                                     .:..||.  ....|.|..|.....|
Human   326 -------------------------CIKYNCTINGVRHCRLLCLVVQYIGEICRYLLKQPVREAE 365

  Fly   307 -GSRAALEVQKGIR--------SRLSHNCLQFVYGFTELGAMATINC---HFDEKTGSVG----- 354
             ..|..|.|..|:|        .|.....:...||.||      .||   :.|.|.||.|
Human   366 RRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATE------CNCSIANMDGKVGSCGFNSRI 424

  Fly   355 -QLVNGLKMKIKNDDGESLGPDEIGEVCI-------------MNNQ----HWSGYYGNEVETRNM 401
             ..|..:::...|:|...|..|..| :||             :|.|    .:.||......::.:
Human   425 LPHVYPIRLVKVNEDTMELLRDAQG-LCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKI 488

  Fly   402 RDSL-----GWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFG 461
            ..|:     ..|.|||:..||..|::|..||..:..:::.......::|.|:|.:....:|.|:|
Human   489 AHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYG 553

  Fly   462 I-WSNIFGDEAAAAV 475
            : ...:.|....|||
Human   554 VAVPGVEGKAGMAAV 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1R	NP_650829.1	Firefly_Luc_like	47..522	CDD:341237	115/527 (22%)
SLC27A1	XP_011526302.1	Adenylate forming domain, Class I superfamily	101..623	CDD:473059	113/520 (22%)