Protein Alignment CG11659 and acs-2

DIOPT Version :9

• Sequence 1: NP_650829.1
• Gene: CG11659 / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_506869.1
• Gene: acs-2 / 3565680
• WormBaseID: WBGene00009221
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 122/597 - (20%)
• Similarity: 237/597 - (39%)
• Gaps: 122/597 - (20%)

  Fly     4 TPENSYDNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMR 68
            |.|...|.:..::|..|:.|.:       |..:|::|                           :
 Worm    68 TTERVPDKEFCVFSKYPIRKTY-------EEFYHDVR---------------------------Q 98

  Fly    69 LASYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIF 133
            :|:.:.:|||.:.|.||:.|.|....:.:.|||.|.|:...::|..|..:.:..:.:.|...::|
 Worm    99 MAASLYTLGLEKGDRVGVWGPNYYEWVVLQYACAFAGVIQVNVNPHYLHEELRFVMRKTGMKVLF 163

  Fly   134 C-----DGDEFEKVRSATAEL---DVKIVTMRNHPLDSIKI-----DEVVATPIE---------- 175
            .     ..:....:..|..|:   ...:..:::|.:..::.     |:|   |:.
 Worm   164 APKRHKHSNYVHTMLEAMPEMRRGQPGVGHIKSHDIPELRHIVLYGDDV---PVHGAWVYSDLIH 225

  Fly   176 --ENFQPAKLEKGN-----DQTLAILCSSGTTGTPKAVTIT----NSRHILAG--------NYHL 221
              .:.:.||||..:     |:.:.:..:|||||.||..|:|    |:....||        ::.:
 Worm   226 AAGSAERAKLEDMDRKLRPDEPVNMQFTSGTTGHPKGATLTHFGLNNNAYFAGIRLGWDREDHRI 290

  Fly   222 TTADVQYSHNTLDWITGLLTTITSGVFSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALM 286
            ...:..|  :......|::..:..|   .|.:....::........|:..|.|.....|:....:
 Worm   291 CIPNPLY--HCFGCAVGVINAVNHG---QTVVFPSKSYHVPDIFEAIQNEKCTTMFGTPTMFIDV 350

  Fly   287 INCPDFETCDLSSLRCYMFGGSRAALEVQKGIRSRLSHNCLQFVYGFTELGAMATIN-CHFD--E 348
            :..|..:..|:||||..:.||:...:.:.:.:...:.......:||.||...:.|:: .|.|  |
 Worm   351 LKSPLMKQFDISSLRGGVIGGAPCPMALCEKMVKEMRMTDFSVIYGSTETSPLVTMSELHVDPFE 415

  Fly   349 KTGSVGQLVNGLKMKIKNDDGESLGPDEIGEVCIMNNQHWS-------GYYGNEVETRNM---RD 403
            :..|||.::...::.|.::.|..:.....||:       ||       ||:.:..:| |:   ||
 Worm   416 RIKSVGSVMPHQELAIVDEFGVPVPTGAKGEL-------WSRGYSTMLGYWADHDKT-NLAITRD 472

  Fly   404 SLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFG 468
            .  ||.|||...|:.||.:.|:.|.::|:.......||.:||..:.::..||:..|.|:..:.:|
 Worm   473 R--WYKSGDTATMNEDGTINIVGRTRDMIVKGGENVYPTEIEQFLHKLDYVADAHVVGVPDDRYG 535

  Fly   469 DEAAAAVVKKLGSE---------------LEAQDVVDYVRSRTDSKYKQLNGGAVIVDDLQRSAN 518
            :...|.|..::..|               :....|..||..:.:|::.....|.|...::|:.:.
 Worm   536 ENICAWVRLRVEDEGKITAEHIKKACKRGMAHYKVPKYVLIKKESEFPLTISGKVKKFEIQKISK 600

  Fly   519 GKTNRMANKAHF 530
            ........|:||
 Worm   601 ELLGLGTVKSHF 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	113/566 (20%)
		AFD_class_I	47..522	CDD:302604	110/544 (20%)
acs-2	NP_506869.1	PRK08315	46..609	CDD:236236	119/592 (20%)
		FACL_like_2	244..595	CDD:213284	81/365 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2257
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760