Protein Alignment CG11659 and ACSM4

DIOPT Version :9

• Sequence 1: NP_650829.1
• Gene: CG11659 / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001073923.1
• Gene: ACSM4 / 341392
• HGNCID: 32016
• Length: 580
• Species: Homo sapiens
• Alignment Length: 505
• Identity: 114/505 - (22%)
• Similarity: 202/505 - (40%)
• Gaps: 71/505 - (14%)

  Fly    60 GELLANAMRLASYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAF--HSLNITYDRDTIEK 122
            |.|...|..:.:  :..||.:.|.:.:|.........|..||...||.|  .::.:| .:|.:.:
Human    95 GSLSRKAANVLT--KPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLT-AKDILYR 156

  Fly   123 IYKVTRPSIIFCDGDEFEKVRSATAE---LDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLE 184
            : :.::...|....:....|.|...|   |..|::.........:...|:.....||:   :.:|
Human   157 L-RASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEH---SCVE 217

  Fly   185 KGNDQTLAILCSSGTTGTPKAVTITNSR----HILAGNY--HLTTADVQYSHNTLDWITGLLTTI 243
            .|:.:.:.|..:|||||.||....:.|.    ..|.|.|  .|.::|:.::.:...|:...:.::
Human   218 TGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSV 282

  Fly   244 TSGVFSTTRIIADN--AFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDLSSLRCYMFG 306
            .|.......:....  .||....|..:..|.:|....||:...:::. .|.:.....|||..:.|
Human   283 FSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQ-KDLKRYKFKSLRHCLTG 346

  Fly   307 GS------------RAALEVQKGIRSRLSHNCLQFVYGFTELGAMATINCHFDEKTGSVGQLVNG 359
            |.            :..||:.:|             ||.||:|.:.......:.|.||:|:.:..
Human   347 GEPLNPEVLEQWRVQTGLELYEG-------------YGQTEVGMICANQKGQEIKPGSMGKGMLP 398

  Fly   360 LKMKIKNDDGESLGPDEIGEVCIMNNQ-----HWSGYYGNEVET-RNMRDSLGWYHSGDLGYMDR 418
            ..::|.:::|..|.|.:.||:.:....     .:|.|..|..:| ..:|..  :|.:||.|.||.
Human   399 YDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGD--FYVTGDRGVMDS 461

  Fly   419 DGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVV------- 476
            ||:.:.:.|..:::........|.::||.:.|.|.|.|..|......|.|:...|.||
Human   462 DGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKS 526

  Fly   477 ---KKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVDDLQRSANGKTNR 523
               :||..||:     |:|:..| :.||... ....|.:|.::..||..|
Human   527 YNPEKLTLELQ-----DHVKKST-APYKYPR-KVEFVQELPKTITGKIKR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	113/503 (22%)
		AFD_class_I	47..522	CDD:302604	113/502 (23%)
ACSM4	NP_001073923.1	MACS_euk	48..577	CDD:213294	114/505 (23%)
		Acs	49..580	CDD:223442	114/505 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920