DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11659 and Acsm2

DIOPT Version :9

Sequence 1:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_001171448.1	Gene:	Acsm2 / 233799	MGIID:	2385289	Length:	600	Species:	Mus musculus

Alignment Length:	501	Identity:	105/501 - (20%)
Similarity:	198/501 - (39%)	Gaps:	85/501 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 GLLQSDIVGLIGRNTTHMLAVAYACFFNGIAFHSLNITY-DRDTIEKIYKVTRPSIIFCDGDEFE 140
            ||.:.|.|.::.........:...|...|:.|....|.. ..|.:.::......:|:  .|||..
Mouse   127 GLHRGDRVAVVLPRIPEWWLMILGCMRTGLVFMPGTIQMRSSDILYRLQASKARAIV--AGDEVA 189

  Fly   141 KVRSATAE----LDVKIVTMRNHPLDSIKIDEVV--ATPIEENFQPAKLEKGNDQTLAILCSSGT 199
            :...|.|.    |.:|::...|.....:....::  |:.|.:     .:|..:.::.||..:|||
Mouse   190 QEVDAVAPDCSFLKIKLLVSENSREGWLNFKALLKEASTIHQ-----CVETESRESAAIYFTSGT 249

  Fly   200 TGTPKAVTITNSRHILAGNYH----------------LTTADVQYSHNTLDWITGLLTTITSGVF 248
            :|.||          :|.:.|                |:|:|:.::.:...||..:|     |.|
Mouse   250 SGPPK----------MAEHSHCSLGIKAKMDAASWTGLSTSDIIWTISDTAWIMNIL-----GAF 299

  Fly   249 STTRIIAD-------NAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDLSSLR----- 301
            ....::..       ..||....|:::..|.:...:..|....:::.      .||||.:
Mouse   300 LEPWVLGACIFVHLLPKFDSQTVLKVLSSYPINTLVGAPIIYRMLLQ------QDLSSYKFPHLH 358

  Fly   302 -CYMFGGSRAALEVQKGIRSRLSHNCLQFVYGFTELGAMATINCHFDEKTGSVGQLVNGLKMKIK 365
             |:. ||.....|..:..:::.... ::.:||.||.|.:..::.....|.|.:|.......:::.
Mouse   359 SCFS-GGETLLPETLENWKAKTGLE-IREIYGQTETGLICRVSRTMKVKPGYLGTAFAHYDVQVI 421

  Fly   366 NDDGESLGPDEIGEVCIMNNQHW-----SGYYGNEVETR-NMRDSLGWYHSGDLGYMDRDGFLYI 424
            ::.|..|.|.:.|::.|.....|     |||..|..:|: |:|... |. .||.|..|.:|:.:.
Mouse   422 DEQGNVLPPGKEGDIAIRVKPIWPIGMFSGYVDNPKKTQDNIRGDF-WL-MGDRGIKDPEGYFHF 484

  Fly   425 MDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQD-- 487
            :.|..:::........|:::|:.:.|.|.|:|..|........|:...|.||  |..|..:.|
Mouse   485 IGRSDDIINSSGYRIGPSEVENALMEHPAVSETAVISSPDPSRGEVVKAFVV--LAPEFLSHDRD 547

  Fly   488 -----VVDYVRSRTDSKYKQLNGGAVIVDDLQRSANGKTNRMANKA 528
                 :.::|:|.| :.||.......:: ||.::..||..|...:|
Mouse   548 QLTKVLQEHVKSVT-APYKYPRKVEFVL-DLPKTVTGKIERAKLRA 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	103/494 (21%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	103/493 (21%)
Acsm2	NP_001171448.1	Acs	65..591	CDD:223442	104/499 (21%)
Acsm2	NP_001171448.1	AFD_class_I	66..594	CDD:302604	105/501 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920