Protein Alignment Acsx1R and DIP2C

DIOPT Version :10

• Sequence 1: NP_650829.1
• Gene: Acsx1R / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: XP_054221234.1
• Gene: DIP2C / 22982
• HGNCID: 29150
• Length: 1626
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 159/662 - (24%)
• Similarity: 248/662 - (37%)
• Gaps: 191/662 - (28%)

  Fly    10 DNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHP-QLTAQISATEGTV---LTRGELLANAMRLA 70
            ||||        .:.|   |.:.|::....:..| .:...:....|.:   ||..:|...|.::|
Human  1022 DNDQ--------ARKF---LFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIA 1075

  Fly    71 SYMRSLGLLQ-SDIVGLIGRNTTHMLAVAYACFFNGIA------FHSLNITYDRDTIEKIYKVTR 128
            ..:...|.|| .|.|.|:......::|..|.|.:.|..      .|..||.....|::.|.:|:|
Human  1076 VMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR 1140

  Fly   129 PSI-----IFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLEKG-N 187
            .:.     :.|   :..:.|.|.|.:||     |..||       ::.|......:||::.|. |
Human  1141 SACLMTTQLIC---KLLRSREAAAAVDV-----RTWPL-------ILDTDDLPKKRPAQICKPCN 1190

  Fly   188 DQTLAIL-CSSGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNT------------------- 232
            ..|||.| .|..|||            :|||        |:.||..
Human  1191 PDTLAYLDFSVSTTG------------MLAG--------VKMSHAATSAFCRSIKLQCELYPSRE 1235

  Fly   233 ----LDWITGL------LTTITSGVFSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMI 287
                ||...||      |.::.||..|.....::...:||..|..:.:|||..|....|.|.|..
Human  1236 VAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCT 1300

  Fly   288 NCPDFET-------CDLSSLR-CYMFGGSR--------------------AALEVQKGIRSRLSH 324
            .....:|       .|||.:| |.:....|                    .|:....|.|..|:
Human  1301 KGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLA- 1364

  Fly   325 NCLQ------------------FVYGFTELGAMATINCHFDEKTGS--------VGQLVNGLKMK 363
            .|||                  .||  .::.|:........|: ||        .|:::.|:::.
Human  1365 ICLQPHRLWTLAEQGTSGPDPTTVY--VDMRALRHDRVRLVER-GSPHSLPLMESGKILPGVRII 1426

  Fly   364 IKNDDGES-LGPDEIGEVCIMNNQHWSGY---YGNE---VETRNMRDSLG-----WYHSGDLGYM 416
            |.|.:.:. ||...:||:.:.:..:.|||   ||:|   .:..|.|.|.|     |..:|.||::
Human  1427 IANPETKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFL 1491

  Fly   417 ----------DRDGFLYIMDRKKEMLKYQNIMYYPNDIE-SVISEMPQVAEVCVFGIWSNIFGDE 470
                      :|...||::....|.::.:.:.|:|.||| |||.....|.|..|| .|:|:.
Human  1492 RRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVF-TWTNLL--- 1552

  Fly   471 AAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVD--DLQRSANGKTNRMANKAHFLHL 533
              ..||:..|||.||.|:|..|.:....::..:.|..|:||  .:..::.|:..||       ||
Human  1553 --VVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRM-------HL 1608

  Fly   534 KNRKNILLSQIN 545
              |...|..|::
Human  1609 --RDGFLADQLD 1618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1R	NP_650829.1	Firefly_Luc_like	47..522	CDD:341237	144/599 (24%)
DIP2C	XP_054221234.1	DMAP_binding	<32..178	CDD:368923
		Dip2	396..972	CDD:341231
		Dip2	1048..1622	CDD:341231	151/625 (24%)