Protein Alignment CG11659 and ACSL1

DIOPT Version :9

• Sequence 1: NP_650829.1
• Gene: CG11659 / 42352
• FlyBaseID: FBgn0038731
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001273637.1
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 135/616 - (21%)
• Similarity: 225/616 - (36%)
• Gaps: 165/616 - (26%)

  Fly    17 SGEPVVKYFDPDLSIGEIIFHEMRRHPQLT-----------------------AQISATEGTVLT 58
            |.||:|.::| |::   .::...:|..|::                       |::|...|:.|.
Human    78 SDEPLVYFYD-DVT---TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALI 138

  Fly    59 RGELLANAMRLASYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKI 123
            :              :.........:|:..:|....:.:...||...:....|..|...:.|..|
Human   139 Q--------------KGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYI 189

  Fly   124 YKVTRPSIIFCDGDEFEKVRSATAE------LDVKIVTMRNHPLDSIKID-----EVVATPIEEN 177
            ......|::|.|..|..|:.....|      |.: ||.|..:..:.::..     ||.:....|:
Human   190 VNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKI-IVVMDAYGSELVERGQRCGVEVTSMKAMED 253

  Fly   178 FQPAKLEKGN---DQTLAILC-SSGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNTL----- 233
            ...|...|..   .:.||::| :|||||.||...:|: |:|::.    .:|.|:.:.||:
Human   254 LGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTH-RNIVSD----CSAFVKATENTVNPCPD 313

  Fly   234 DWITGLLTTITSGVFSTTRII--------ADNAFDPAFALRIIEEYKVTWTIQP---PSSMALMI 287
            |.:...|.  .:.:|.  |::        |...|.......::::.||   :||   |....|:.
Human   314 DTLISFLP--LAHMFE--RVVECVMLCHGAKIGFFQGDIRLLMDDLKV---LQPTVFPVVPRLLN 371

  Fly   288 NCPD--FETCDLSSLRCYM-FGGSRAALEVQKGI---------------------RSRL------ 322
            ...|  |...:.:..|..: |...|...|::.||                     |.||
Human   372 RMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAA 436

  Fly   323 --SHNCLQFV-----------YGFTELGAMATINCHFDEKTGSVG--------QLVNGLKMKIKN 366
              |...|.|:           ||.||..|...:....|...|.||        :||:..:|....
Human   437 PVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMA 501

  Fly   367 DDGESLGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEM 431
            .:||       ||||:.....:.||..:..:|....|..||.|:||:|....:|.|.|:||||.:
Human   502 AEGE-------GEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHI 559

  Fly   432 LKYQNIMYY-PNDIESVISEMPQVAEVCVFG------IWSNIFGD-EAAAAVVKKLGSELEAQDV 488
            .|.....|. |..||::......||:|.|.|      :.:.:..| |...:..:|.|.|...:::
Human   560 FKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624

  Fly   489 V-----------DYVRSRTDS---KYKQLNG 505
            .           |.||...||   .::|:.|
Human   625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKG 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	131/607 (22%)
		AFD_class_I	47..522	CDD:302604	127/563 (23%)
ACSL1	NP_001273637.1	LC-FACS_euk	116..694	CDD:341250	127/574 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.930