DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11659 and Acsl6

DIOPT Version :9

Sequence 1:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	XP_030101662.1	Gene:	Acsl6 / 216739	MGIID:	894291	Length:	748	Species:	Mus musculus

Alignment Length:	549	Identity:	123/549 - (22%)
Similarity:	186/549 - (33%)	Gaps:	172/549 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RHPQLTAQ-ISATEGTVLTRGELLANAMRLASYMRSLGLLQSD-------IVGLIGRNTTHMLAV 97
            |.|:...| :|..|  |..|.|.|.:           ||||.|       .||:..:|....:..
Mouse   137 RKPEQPYQWLSYQE--VAKRAEFLGS-----------GLLQHDCKVGTEQFVGVFAQNRPEWIIA 188

  Fly    98 AYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELD---------VKI 153
            ..||:...:....|..|....:|..|........:..|     |...||..|:         :|:
Mouse   189 ELACYTYSMVVVPLYDTLGPGSISYIINTADICTVIVD-----KPHKATLLLEHVERKETPGLKL 248

  Fly   154 VTMRNHPLDSIK-------IDEVVATPIE----ENFQPAKLEKGNDQTLAILC-SSGTTGTPKAV 206
            |.:.....|:::       :|......||    ||.......:.:|  |:|:| :|||||.||..
Mouse   249 VILMEPFEDALRERGKKCGVDIKSMQAIEDCGRENHHAPVPPRPDD--LSIVCFTSGTTGNPKGA 311

  Fly   207 TITNS-----------------------------------RHILAGNYHLTTADVQYSHNTLDWI 236
            .:|:.                                   ..::...:..|.|||.:|:..|..:
Mouse   312 MLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSQWAPTCADVHFSYLPLAHM 376

  Fly   237 TGLLTTITSGVF----------STTRIIADN--AFDPAFALRIIEEYKVTWTIQP--PSSMALMI 287
            ...:  :.|.|:          ...|:::|:  |..|              ||.|  |..:..|.
Mouse   377 FERM--VQSVVYCHGGRVGFFQGDIRLLSDDMKALRP--------------TIFPVVPRLLNRMY 425

  Fly   288 NCPDFETCDLSSLRCYM-FGGSRAALEVQKGI-----------------------------RSRL 322
            : ..|...|.|..|..: |...|...||:.||                             .:..
Mouse   426 D-KIFHQADTSLKRWLLEFAAKRKQAEVRSGIIRNNSIWDELFFNKIQASLGGHVRMIVTGAAPA 489

  Fly   323 SHNCLQFV-----------YGFTELGAMATINCHFDEKTGSVG--------QLVNGLKMKIKNDD 368
            |...|.|:           ||.||..|..|.....|..:|.||        :||:..::......
Mouse   490 SPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTCK 554

  Fly   369 GESLGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLK 433
            ||       ||:|:.....:.||..:|..|:...||.||.|:||:|....:|.|.|:||||.:.|
Mouse   555 GE-------GEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFK 612

  Fly   434 YQNIMYY-PNDIESVISEMPQVAEVCVFG 461
            .....|. |..||::......||::.|.|
Mouse   613 LAQGEYVAPEKIENIYIRSEPVAQIYVHG 641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	123/549 (22%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	121/543 (22%)
Acsl6	XP_030101662.1	LC-FACS_euk	141..744	CDD:341250	121/545 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839195
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930