DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11659 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	561	Identity:	121/561 - (21%)
Similarity:	208/561 - (37%)	Gaps:	139/561 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 AMRLASYMRSLGLLQSDIVGLIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPS 130
            |.::|.....|||.::..|.::|.|:......|....|.|.....:..|...:..:.|....|.:
  Rat   139 ARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRAN 203

  Fly   131 IIFCDGD-EFEKVRSATAEL-DVKIVTMRNHP----------LDSI-----KIDEVVATPIEENF 178
            :|..|.. :.||:.....:| .:|.|.:...|          ::.:     ::.|.....|.:..
  Rat   204 VIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALDAIIDTQ 268

  Fly   179 QPAKLEKGNDQTLAILCSSGTTGTPKAVTITNSR------------------------------- 212
            ||       :|...::.:|||||.||.|.::...
  Rat   269 QP-------NQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLS 326

  Fly   213 HILAGNYHLTTADVQYSHNTL----DWITGLLTTITSGVFSTTRI--------IADNAFDPAFAL 265
            ||.|..|.|.|. :|:.....    |.:.|.|......|..|:.:        |.:...:.|...
  Rat   327 HIAAQIYDLWTG-IQWGAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQS 390

  Fly   266 RIIEEYKVTWTIQPPSSMALMIN--CPDFETCDLSS-----------------LRCY--MFGGSR 309
            ..|....:.|.:    |:.|..|  ||..:....:|                 .:|.  .:|.:.
  Rat   391 GFIRRKMLLWAM----SVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAP 451

  Fly   310 AALEVQK---GIRSRLSHNCLQFVYGFTELGAMATINCHFDEKTGSVGQLVNGLKMKIKNDDGES 371
            ...|.|:   |:..||...     ||.:|......::..::.:..|.|::|.|.::|:.|.|.
  Rat   452 MTAETQRFFLGLNIRLYAG-----YGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLVNQDA-- 509

  Fly   372 LGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEML---K 433
               |.|||:|:.....:.||...|.:|....||.||.|:||:|.:|.||||||..|.||::   .
  Rat   510 ---DGIGEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDMGRLDDDGFLYITGRLKELIITAG 571

  Fly   434 YQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFG--------------------DEAAAAVVKK 478
            .:|:...|.: |:|..|:|.::...:.|.......                    .|.|....::
  Rat   572 GENVPPVPIE-EAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETSEPTDNLTEQAVEFCQR 635

  Fly   479 LGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVDDLQR-SAN 518
            :||  :|..|.:.|..:.::.|:.::.|      :|| :||
  Rat   636 VGS--KASTVSEIVGQKDEAVYQAIHEG------IQRVNAN 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	121/561 (22%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	121/561 (22%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	121/561 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930