DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11659 and Acsl3

DIOPT Version :9

Sequence 1:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_476448.1	Gene:	Acsl3 / 114024	RGDID:	70552	Length:	720	Species:	Rattus norvegicus

Alignment Length:	502	Identity:	111/502 - (22%)
Similarity:	180/502 - (35%)	Gaps:	168/502 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PQLTAQISATEGT-VLTRGELLANAMRLASYMRSLGLLQSDIVGLIGRNTTHMLAV-----AYAC 101
            |.:...::.||.| ::|..|||...::             |||.|:.| ..|::.|     .::.
  Rat   196 PAIVHGLNETEVTNIITSKELLQTKLK-------------DIVSLVPR-LRHIITVDGKPPTWSE 246

  Fly   102 FFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKI-VTMRNH--PLDS 163
            |..|:..|::                                :|...|.||. |..:.|  ||.|
  Rat   247 FPKGVIVHTM--------------------------------AAVQALGVKADVDKKAHSKPLPS 279

  Fly   164 IKIDEVVATPIEENFQPAKLEKGNDQTLAILCSSGTTGTPKAVTITNSRHI--LAGNY----HLT 222
                                     ....|:.:||:||.||.|.|::|..|  :.|..    .|.
  Rat   280 -------------------------DIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLG 319

  Fly   223 TADVQYSHNTLDWITGL---LTTITSGV---FSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPS 281
            ..||...:..|..:..|   |..::.|.   :|:.:.:||.      :.:|.:..|...::..|:
  Rat   320 EEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ------SSKIKKGSKGDTSVLKPT 378

  Fly   282 SMALMINCPD---------------FE----------------------TCDL-----------S 298
            .||.:....|               |:                      .||.           .
  Rat   379 LMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGG 443

  Fly   299 SLRCYMFGGSRAALEVQKGIRSRLSHNCLQFV------YGFTELGAMATINCHFDEKTGSVGQLV 357
            ::|..:.||:..:...|     |..:.|  |.      ||.||.....||...:|..||.||..:
  Rat   444 NIRVLLCGGAPLSATTQ-----RFMNIC--FCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPL 501

  Fly   358 NGLKMKIKN-DDGESLGPDE---IGEVCIMNNQHWSGYYGNEVETRN--MRDSLG--WYHSGDLG 414
            ...::|:|| ::|.....|:   .||:.|.......|||.||.:|:.  ..|..|  |..:||:|
  Rat   502 VCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIG 566

  Fly   415 YMDRDGFLYIMDRKKEMLKYQNIMYYP-NDIESVISEMPQVAEVCVF 460
            ..|.||.|.|:||||:::|.|...|.. ..:|:.:..:|.:..:|.:
  Rat   567 EFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAY 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	111/502 (22%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	110/498 (22%)
Acsl3	NP_476448.1	PLN02387	30..717	CDD:215217	111/502 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930