DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6300 and 4CL3

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_176686.1	Gene:	4CL3 / 842814	AraportID:	AT1G65060	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	145/560 - (25%)
Similarity:	255/560 - (45%)	Gaps:	54/560 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ENSYDNDQKIWSGEPVVKYFD---PDLSIGEII------FHEMRRHPQLTAQISATEGTVLTRGE 61
            :.|..:|..:....|..:.|.   ||:.|...:      |.::.........|..:.|...|.||
plant    16 DTSVVSDDVLPHSPPTPRIFRSKLPDIDIPNHLPLHTYCFEKLSSVSDKPCLIVGSTGKSYTYGE 80

  Fly    62 LLANAMRLASYMRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKV 126
            ......|:||.:..||:.:.|::.|:.:|:...:.........|....:.|..|   |.:::||.
plant    81 THLICRRVASGLYKLGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFY---TSQELYKQ 142

  Fly   127 TRPS---IIFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLEKGND 188
            .:.|   :|.......:|:::....|.: |.|....|.:.:....::.......||.. ::.|.|
plant   143 LKSSGAKLIITHSQYVDKLKNLGENLTL-ITTDEPTPENCLPFSTLITDDETNPFQET-VDIGGD 205

  Fly   189 QTLAILCSSGTTGTPKAVTITNSRHILA---------GNYHLTTADV---------QYSHNTLDW 235
            ...|:..||||||.||.|.:|:...|.:         .|.:|.:.||         .||.|::
plant   206 DAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKSNDVILCVLPLFHIYSLNSV-- 268

  Fly   236 ITGLLTTITSGVFSTTRIIADNAFDPAFALRIIEEYKVT-WTIQPPSSMALMINCPDFETCDMSS 299
               ||.::.||    ..::..:.|:....|.:|:.::|| ..:.||..:||..| |...:.|:||
plant   269 ---LLNSLRSG----ATVLLMHKFEIGALLDLIQRHRVTIAALVPPLVIALAKN-PTVNSYDLSS 325

  Fly   300 LRCYMFGGSRAALEVQKGIRSRLSHDCLQFVYGFTELGAMATINCHFDE-----KTGSVGQLVNG 359
            :|..:.|.:....|:|..:|.||....|...||.||.|.:.:::..|.:     |:||.|.:|..
plant   326 VRFVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRN 390

  Fly   360 LKMKIIN-DDGESLGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLY 423
            .::|::: :...|||.::.||:||...|....|..:...|....|..||.|:||:||:|.|..::
plant   391 AELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIF 455

  Fly   424 IMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDV 488
            |:||.||::|::.....|.::||::.....:|:..|......:.|:...|.||:..|:::..:||
plant   456 IVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEDV 520

  Fly   489 VDYVRSRTDSKYKQLNGGAVIVDDLQRSANGKTNRMANKA 528
            .:||..:. ..||:|: ....|..:.:|.:||..|...||
plant   521 KEYVAKQV-VFYKRLH-KVFFVASIPKSPSGKILRKDLKA 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	138/533 (26%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	134/502 (27%)
4CL3	NP_176686.1	PLN02246	26..561	CDD:215137	143/550 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920