DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and 4CL1

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_175579.1	Gene:	4CL1 / 841593	AraportID:	AT1G51680	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	137/547 - (25%)
Similarity:	245/547 - (44%)	Gaps:	34/547 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ENSYDNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLA 70
            :::.:|...|:..:....|....||:.:.||..:.........|:...|.|.|..::...:.::|
plant    15 QSNNNNSDVIFRSKLPDIYIPNHLSLHDYIFQNISEFATKPCLINGPTGHVYTYSDVHVISRQIA 79

  Fly    71 SYMRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCD 135
            :....||:.|:|:|.::..|....:....|..|.|....:.|..:....|.|..|.:...:|..:
plant    80 ANFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNTKLIITE 144

  Fly   136 GDEFEKVRSATAELDVKIVTMRNH-----PLDSIKIDEVVATPIEENFQPAKLEKGNDQTLAILC 195
            ....:|::....:..|.||.:.::     |...::..|:..:..|.:.....:|...|..:|:..
plant   145 ARYVDKIKPLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQSTTEASEVIDSVEISPDDVVALPY 209

  Fly   196 SSGTTGTPKAVTITNSRHILA---------GNYHLTTADVQYSHNTLDWITGLLTTITSGVFSTT 251
            ||||||.||.|.:|:...:.:         .|.:..:.||......:..|..|.:.:..|:....
plant   210 SSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGA 274

  Fly   252 RIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAALEVQK 316
            .|:....|:....|.:|:..|||.....|..:..:....:.|..|:||:|....|.:....|::.
plant   275 AILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLSSIRVVKSGAAPLGKELED 339

  Fly   317 GIRSRLSHDCLQFVYGFTELGAMATINCHFDE-----KTGSVGQLVNGLKMKIIN-DDGESLGPD 375
            .:.::..:..|...||.||.|.:..::..|.:     |:|:.|.:|...:|||:: |.|:||..:
plant   340 AVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRN 404

  Fly   376 EIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYY 440
            :.||:||..:|...||..|...|....|..||.|:||:|.:|.|..|:|:||.||::||:.....
plant   405 QPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVA 469

  Fly   441 PNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLN- 504
            |.::|:::...|.:.:|.|..:.....|:...|.|||...|||...||..:| |:....||::|
plant   470 PAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDDVKQFV-SKQVVFYKRINK 533

  Fly   505 -----------GGAVIVDDLQ-RSANG 519
                       .|.::..||: :.|||
plant   534 VFFTESIPKAPSGKILRKDLRAKLANG 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	134/527 (25%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	130/506 (26%)
4CL1	NP_175579.1	PLN02246	16..560	CDD:215137	135/544 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920