DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and AAE5

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_197141.1	Gene:	AAE5 / 831498	AraportID:	AT5G16370	Length:	552	Species:	Arabidopsis thaliana

Alignment Length:	572	Identity:	117/572 - (20%)
Similarity:	210/572 - (36%)	Gaps:	185/572 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 TVLTRGELLANAMRLASYMRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDT 119
            ||.|..|.....:|:||.:.|:|:.:||:|.::..||..|..:.:|...:|...:::|...|..|
plant    39 TVYTWRETNLRCLRVASSLSSIGIGRSDVVSVLSPNTPAMYELQFAVPMSGAILNNINTRLDART 103

  Fly   120 IEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLE 184
            :..:.:.....::|.|        ..:.:|.|:.::|       :..|..:...|.:     |.|
plant   104 VSVLLRHCGSKLLFVD--------VFSVDLAVEAISM-------MTTDPPILVFIAD-----KEE 148

  Fly   185 KGNDQTLA---------------------------------ILCSSGTTGTPKAVTITNSRHILA 216
            :|.|..:|                                 :..:||||..||.|.     |...
plant   149 EGGDADVADRTKFSYTYDDLIHRGDLDFKWIRPESEWDPVVLNYTSGTTSAPKGVV-----HCHR 208

  Fly   217 GNYHLTTADVQYSHNTLDWITGLLTTITSGVFS-TTRIIADNA-------------------FDP 261
            |.:      |....:.:||     |...:.|:. |..|...|.                   ||.
plant   209 GIF------VMSIDSLIDW-----TVPKNPVYLWTLPIFHANGWSYPWGIAAVGGTNVCLRKFDA 262

  Fly   262 AFALRIIEEYKVTWT-----------------------------IQPPSSMALMINCPDF----- 292
            ....|:|.::.||..                             ..||:::.|......|
plant   263 PLIYRLIRDHGVTHMCGAPVVLNMLSATNEFQPLNRPVNILTAGAPPPAAVLLRAESIGFVISHG 327

  Fly   293 ----ETCDMSSLRC-------YMFGGSRAALEVQKGIRSRLSHDCLQFVYGFTELGAMATINCHF 346
                ||..: ::.|       .:....||.|:.::|:|:          .||||:..:
plant   328 YGLTETAGL-NVSCAWKPQWNRLPASDRARLKARQGVRT----------VGFTEIDVV------- 374

  Fly   347 DEKTGSVGQLVNGLKMKIINDDGESLGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSG 411
            |.::|           :.:..:||:     :||:.:..:....||..:.|.|.....: ||:::|
plant   375 DPESG-----------RSVERNGET-----VGEIVMRGSSIMLGYLKDPVGTEKALKN-GWFYTG 422

  Fly   412 DLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVV 476
            |:|.:..||:|.|.||.|:::..........::|:|:...|.|.||.|.......:|:...|.|.
plant   423 DVGVIHSDGYLEIKDRSKDIIITGGENVSSVEVETVLYTNPAVNEVAVVARPDVFWGETPCAFVS 487

  Fly   477 KKLG-----SELEAQDVVDYVRSRTDSKY---KQLNGGAVIVDDLQRSANGK 520
            .|.|     :|:|   :::|.|.:. .||   |.::    .||:|.:::.||
plant   488 LKSGLTQRPTEVE---MIEYCRKKM-PKYMVPKTVS----FVDELPKTSTGK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	117/572 (20%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	117/572 (20%)
AAE5	NP_197141.1	ttLC_FACS_AEE21_like	12..539	CDD:341283	117/572 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810