DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6300 and 4CL2

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_188761.1	Gene:	4CL2 / 821678	AraportID:	AT3G21240	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	554	Identity:	144/554 - (25%)
Similarity:	253/554 - (45%)	Gaps:	51/554 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NDQKIWSGEPVVKYFDPD------LSIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRL 69
            ||||..|.:.:.:...||      |.:.:.||..:.........|:...|.|.|..::...:.:|
plant    12 NDQKQCSNDVIFRSRLPDIYIPNHLPLHDYIFENISEFAAKPCLINGPTGEVYTYADVHVTSRKL 76

  Fly    70 ASYMRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFC 134
            |:.:.:||:.|.|:|.|:..|:..::....|..|.|....|.|..:....|.|..|.:...:|..
plant    77 AAGLHNLGVKQHDVVMILLPNSPEVVLTFLAASFIGAITTSANPFFTPAEISKQAKASAAKLIVT 141

  Fly   135 DGDEFEKVRSATAELDVKIVTMRNH--PLDSIKIDEVVAT------PIEENFQPAKLEKGNDQTL 191
            .....:|:::...: .|.|||..:.  |.:.::..|:..:      .|.|...|       :..:
plant   142 QSRYVDKIKNLQND-GVLIVTTDSDAIPENCLRFSELTQSEEPRVDSIPEKISP-------EDVV 198

  Fly   192 AILCSSGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNTLDWITGLLT-----TITSGVFSTT 251
            |:..||||||.||.|.:|:...:.:....:...:.....|..|.|..:|.     .:.|.:..:.
plant   199 ALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNRDDVILCVLPMFHIYALNSIMLCSL 263

  Fly   252 RIIADNAFDPAFALRI----IEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAAL 312
            |:.|.....|.|.:.:    |:..|||..:..|..:..:...|:.|..|:||:|....|.:....
plant   264 RVGATILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKSGAAPLGK 328

  Fly   313 EVQKGIRSRLSHDCLQFVYGFTELGAMATINCHFDE-----KTGSVGQLVNGLKMKIIN-DDGES 371
            |::..|.::..:..|...||.||.|.:..::..|.:     |:|:.|.:|...:|||:: |.|:|
plant   329 ELEDAISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDS 393

  Fly   372 LGPDEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQN 436
            |..::.||:||..||...||..:.:.|.:..|..||.|:||:|::|.|..|:|:||.||::||:.
plant   394 LPRNKPGEICIRGNQIMKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDRLKELIKYKG 458

  Fly   437 IMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTDSKYK 501
            ....|.::||::...|::.:|.|..:.....|:...|.||:...|.:...::..:| |:....||
plant   459 FQVAPAELESLLIGHPEINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFV-SKQVVFYK 522

  Fly   502 QLN------------GGAVIVDDLQ-RSANGKTN 522
            ::|            .|.::..||: |.|||..|
plant   523 RINKVFFTDSIPKAPSGKILRKDLRARLANGLMN 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	139/539 (26%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	133/510 (26%)
4CL2	NP_188761.1	PLN02246	14..553	CDD:215137	139/547 (25%)
4CL2	NP_188761.1	4CL	32..546	CDD:213272	130/522 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920