Protein Alignment CG6300 and ACSF2

DIOPT Version :9

• Sequence 1: NP_650828.1
• Gene: CG6300 / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001275897.1
• Gene: ACSF2 / 80221
• HGNCID: 26101
• Length: 640
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 132/544 - (24%)
• Similarity: 235/544 - (43%)
• Gaps: 64/544 - (11%)

  Fly    30 SIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLASYMRSLGLLQSDIVGIIGRNTTHM 94
            ::|:.:....:|.|:..|.:...|...||..:|.....:.||.:.|:||.:.|.:|:.|.|:...
Human    98 TVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAW 162

  Fly    95 LAVAYACFFNGIAFHSLNITYDRDTIEKIY-KVTRPSIIF----------------CDGDEFEKV 142
            :.:..|....||...|:|..|....:|.:. ||...:::|                |  .|.|..
Human   163 VLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQIC--PEVENA 225

  Fly   143 RSATAEL----DVKIVTMRNHPL-DSIKIDEVVATPIEENFQPAKLEKGNDQTLA------ILCS 196
            :....:.    |:..|...:.|| .::.:|||||.  ....|.....:.|.|.|:      |..:
Human   226 QPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAA--GSTRQHLDQLQYNQQFLSCHDPINIQFT 288

  Fly   197 SGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNTLDWITGLLT------------TITSGVFS 249
            |||||:||..|:  |.:.:..|.::....::....|.:.:..:|.            |:...::.
Human   289 SGTTGSPKGATL--SHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYG 351

  Fly   250 TTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAALEV 314
            .|.|:|...|:...||..|...:.|:....|:....::|.|||.:.|:|::...:..||.|..|:
Human   352 ATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPEL 416

  Fly   315 QKGIRSRLSHDCLQFVYGFTELGAMATINCHF-----DEKTGSVGQLVNGLKMKIINDDGESLGP 374
            .:.|.::::...|...||.||...:..  .||     ::|..|||:::...:.:|:|.:..:|..
Human   417 IRAIINKINMKDLVVAYGTTENSPVTF--AHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAK 479

  Fly   375 -DEIGEVCIMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIM 438
             :..||:||.......||:|...:|....|...||.:||:..|:..||..|:.|.|:|:......
Human   480 LNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGEN 544

  Fly   439 YYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTD----SK 499
            .||.::|......|:|.||.|.|:..:..|:|..|.:..|.|.|...:::..:.:.:..    .|
Human   545 IYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPK 609

  Fly   500 YKQLNGGAVIVDDLQRSANGKTNR 523
            |      .|.|.:...:.:||..:
Human   610 Y------IVFVTNYPLTISGKIQK 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	132/542 (24%)
		AFD_class_I	47..522	CDD:302604	129/524 (25%)
ACSF2	NP_001275897.1	PRK08315	82..640	CDD:236236	132/544 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810