DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and slc27a1b

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001070716.1	Gene:	slc27a1b / 553512	ZFINID:	ZDB-GENE-061013-672	Length:	648	Species:	Danio rerio

Alignment Length:	520	Identity:	119/520 - (22%)
Similarity:	198/520 - (38%)	Gaps:	117/520 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLASYMRSLGLLQSDIVGIIGRNTTHM 94
            :|..:....:..||:..|.:..:.|.|.:..||...:..:|.::.:.|....|:|.|...:...|
Zfish    79 TIPSLFAQRVALHPEKAALVDESSGEVWSFSELDRRSNAVAQWVLAQGWRSGDVVAIFMESRPQM 143

  Fly    95 LAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGDEFEKVRSAT-----AELDVKIV 154
            :|:.......|:....:|....||           |:|.|.|     |..|.     ||| :.:|
Zfish   144 VALWLGMAKVGVEPALINFNLRRD-----------SLIHCMG-----VSGACGMVFGAEL-LDVV 191

  Fly   155 TMRNHPLDSIKIDEVVATPIE--ENFQPAKLE----------------KGNDQTLAILCSSGTTG 201
            ......|.|:.:....:.|.|  ::...|.|:                ||.:..|..:.:|||||
Zfish   192 LEVRESLRSLSLFSCGSAPAEMLDSLSAADLDALLSKSPETPPAVAHNKGFNDRLFYIYTSGTTG 256

  Fly   202 TPKAVTITNSRH--ILAGNYH---LTTADVQYS----HNTLDWITGL-------LTTITSGVFST 250
            .|||..:.:||:  |.|.:|:   |...||.|.    :::...|.|:       ||.:....||.
Zfish   257 LPKAAIVVHSRYYRIAAFSYYSFGLQPDDVVYCCLPLYHSAGNIIGVGQCLLHGLTVVIRRKFSA 321

  Fly   251 TRIIADNAFDPAFALRIIEE---YKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAAL 312
            :|...|........::.|.|   |.::..::|..|              :..:|..|..|.|.
Zfish   322 SRFWDDCVKYNCTVVQYIGEICRYLLSQPVRPSES--------------LHRVRVAMGNGLRP-- 370

  Fly   313 EVQKGIRSRLSHDCLQFVYGFTELGAMATINC---HFDEKTGSVGQLVNGL-------------- 360
            .|.:....|.|...:...||.||      .||   :.|.|.|:.|  .|.:
Zfish   371 NVWESFMKRFSVKRIGEFYGATE------CNCSLANMDNKVGACG--FNSVVLPSVYPIRLLRAD 427

  Fly   361 --KMKIINDDGESLGPDEIGEVCI----MNNQ----HWSGYYGNEVETRNM-----RDSLGWYHS 410
              .|::|.|......|.:.||..|    :|.|    .:.||...|..::.:     |.....|.|
Zfish   428 EDTMELIRDSRGLCVPCKPGEPGIIVGRINPQDPLRRFDGYANEEATSKKISHNVFRKGDSAYVS 492

  Fly   411 GDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAV 475
            |||..||..|::|..||..:..:::.......::|.|:|.:.:..:|.|:|:  ::.|.|..|.:
Zfish   493 GDLMVMDELGYVYFRDRGGDTFRWRGENVSTTEVEGVLSALLKQTDVAVYGV--SVPGVEGKAGM 555

Fly 476 475
Zfish 556 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	119/520 (23%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	116/503 (23%)
slc27a1b	NP_001070716.1	PRK08279	60..648	CDD:236217	119/520 (23%)
slc27a1b	NP_001070716.1	AFD_class_I	103..613	CDD:302604	115/496 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930