DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and Acsm1

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001101972.2	Gene:	Acsm1 / 361638	RGDID:	1306813	Length:	577	Species:	Rattus norvegicus

Alignment Length:	541	Identity:	124/541 - (22%)
Similarity:	198/541 - (36%)	Gaps:	128/541 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 ELLANAMRLAS-YMRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAF-------HSLNITYDR 117
            ||...:.|.|: :.::.||...|.:.:|.........|...|...|:.|       .:.:|.|..
  Rat    90 ELRDLSRRAANVFEQTCGLQHGDRLALILPRVPEWWLVTVGCIRTGVIFIPGTAQMKAKDILYRI 154

  Fly   118 DTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKIVTM-RNHPLDSIKIDEVVATPIEE---NF 178
            ...:....||..|::    .|.|.|.|....|..|||.. .||                |   ||
  Rat   155 QMSQAKAIVTTDSLV----PEVESVASECPGLKTKIVVSDHNH----------------EGWLNF 199

  Fly   179 QPAKLEKGNDQT---------LAILCSSGTTGTPKAV----------TITNSRHILAGNYHLTTA 224
            :........|.|         :.|..:|||||.||..          ::.:.|..|    .|.|:
  Rat   200 RTLLRSASPDHTCVKSKMKDPMVIFFTSGTTGYPKMAKHNQGLAFRSSVPSCRKFL----KLKTS 260

  Fly   225 DVQYSHNTLDWITG----LLTTITSGVFSTTRIIADN--AFDPAFALRIIEEYKVTWTIQPPS-- 281
            ||.:..:...||..    ||...|:|    ..:...|  .|||...:..:.:|.:|..:..|:
  Rat   261 DVIWCMSDPGWILATVGCLLEPWTAG----ATVFVHNLPQFDPKVIVETLFKYPITQCLAAPAVY 321

  Fly   282 SMALMINC-----PDFETCDMSSLRCYMFGGSRAALEVQKGIRSRLS---HDCLQFVYGFTELGA 338
            .|.|..|.     |..|.|        ..||.....|..:..:.|..   |:    |||.:|.|.
  Rat   322 RMVLQKNISNLRFPTLEHC--------ATGGESLLPEEYEQWKQRTGLSIHE----VYGQSETGI 374

  Fly   339 MATINCHFDEKTGSVGQLVNGLKMKIINDDGESLGPDEIGEVCIMNNQHWSGYYGNEVE-TRNMR 402
            ...|......|.||:|:.:....::||::.|..|.|:.            .||.|..:: ||.:.
  Rat   375 TCAIFREMKVKRGSIGKAILPFDIQIIDEKGNILPPNT------------EGYIGIRIKPTRPLG 427

  Fly   403 DSLGW---------------YHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMP 452
            ..:|:               |:|||...:|.||:::.:.|..:::........|.::|:.:.|.|
  Rat   428 LFVGYENSPEKTSEVECGDFYNSGDRATIDEDGYIWFLGRSDDVINASGYRIGPTEVENALVEHP 492

  Fly   453 QVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQD-------VVDYVRSRTDSKYKQLNGGAVIV 510
            .|:|..|........|:...|.:|  |..|..:.|       :.::|:|.| :.||... ....|
  Rat   493 AVSESAVVSSPDKDRGEVVKAFIV--LNPEFLSHDQEQLIKELQEHVKSVT-APYKYPR-KVEFV 553

  Fly   511 DDLQRSANGKTNR--MANKAY 529
            .:|.::..||..|  :.||.:
  Rat   554 SELPKTITGKIKRKELRNKEF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	121/531 (23%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	121/530 (23%)
Acsm1	NP_001101972.2	AFD_class_I	46..573	CDD:302604	123/538 (23%)
Acsm1	NP_001101972.2	Acs	46..570	CDD:223442	122/535 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010