DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and AgaP_AGAP003482

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_560023.4	Gene:	AgaP_AGAP003482 / 3290850	VectorBaseID:	AGAP003482	Length:	545	Species:	Anopheles gambiae

Alignment Length:	532	Identity:	144/532 - (27%)
Similarity:	257/532 - (48%)	Gaps:	64/532 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLASYMRSLGLLQSDIVGIIGRNTTHM 94
            |:||:|...:.|:....|.|....|..||..::||.:::||:....||:.::.:|||...|:...
Mosquito    26 SVGELIVKRLNRNGDEVALIDGVSGATLTYHQILARSLKLANRFHRLGIKRNSVVGICSENSVQF 90

  Fly    95 LAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKIVTMRNH 159
            ..:.:|....|.....:|..|....::.:.::|:|..:|......:           ||||:||
Mosquito    91 PIITFATLMLGGTVLPINYGYSEVELQHVLQLTKPIALFASEQPLQ-----------KIVTIRN- 143

  Fly   160 PLDSIKI---------DEVVATPIEENF-------------QPAKLEKGNDQTLAILCSSGTTGT 202
            .|.|:|:         ...:|. :|:.|             ||..|.:   |...::.||||||.
Mosquito   144 VLPSVKLLVSLGKQRPSRGIAL-LEDFFDNSPPGSLHSFTPQPVPLRQ---QVAVMVMSSGTTGL 204

  Fly   203 PKAVTITNSRHILAGNYHLTTADVQYSHNTLD----------WITGLLTTITSGVFSTTRIIADN 257
            ||||.:|:...:....|.  ..|.:|:...:.          .:.|.:.::.|.:.....::...
Mosquito   205 PKAVQLTHHNVMTVMAYQ--AEDPRYTELPVPVRVLGLLPFYHVFGFMLSLNSCLNKVPMVVLPR 267

  Fly   258 AFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAALEVQKGIRSRL 322
             |:|...||.|:.:::|.....|..:..:...|..:..|:|||...:.|.:..:.|:::.::|||
Mosquito   268 -FEPDLFLRTIQNHRITMASLVPPLVVFLAKSPLTQGYDLSSLHALLCGAAPLSREIEELVQSRL 331

  Fly   323 SHDCLQFV---YGFTE--LGAMATINCHFDEKTGSVGQLVNGLKMKIIN-DDGESLGPDEIGEVC 381
            .:  :|.|   ||.:|  ||.::.:|    :|.||||::.....:|::: :.|.:|||::.||:|
Mosquito   332 PN--VQTVRTGYGMSETSLGVISRMN----DKVGSVGKVHKTTYVKVVDLETGCALGPNQTGEIC 390

  Fly   382 IMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIES 446
            :.......||..|:..|..:.|:.||.|:||:||.|.:...:|:||.|:::||:.....|.::|.
Mosquito   391 VKGPLVMKGYLHNDRATGEIIDADGWLHTGDVGYYDEEQDFFIVDRIKDLIKYKGFQVPPAELED 455

  Fly   447 VISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVD 511
            |:....||.:..|.|:...:.|:..||.||.:.|..:.|.::..||.|:. |..|||.||...||
Mosquito   456 VLLSHRQVRDCAVVGVPDEMAGELPAAFVVLQAGESVTANEIERYVASKL-SPQKQLRGGVFFVD 519

  Fly   512 DLQRSANGKTNR 523
            ::.::.:||..|
Mosquito   520 EIPKTGSGKILR 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	143/530 (27%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	138/512 (27%)
AgaP_AGAP003482	XP_560023.4	Firefly_Luc_like	43..530	CDD:213279	138/512 (27%)
AgaP_AGAP003482	XP_560023.4	CaiC	26..544	CDD:223395	144/532 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820