Protein Alignment CG6300 and DIP2C

DIOPT Version :9

• Sequence 1: NP_650828.1
• Gene: CG6300 / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_011517730.1
• Gene: DIP2C / 22982
• HGNCID: 29150
• Length: 1626
• Species: Homo sapiens
• Alignment Length: 648
• Identity: 153/648 - (23%)
• Similarity: 245/648 - (37%)
• Gaps: 182/648 - (28%)

  Fly    10 DNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHP-QLTAQISATEGTV---LTRGELLANAMRLA 70
            ||||        .:.|   |.:.|::....:..| .:...:....|.:   ||..:|...|.::|
Human  1022 DNDQ--------ARKF---LFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIA 1075

  Fly    71 SYMRSLGLLQ-SDIVGIIGRNTTHMLAVAYACFFNGIA------FHSLNITYDRDTIEKIYKVTR 128
            ..:...|.|| .|.|.::......::|..|.|.:.|..      .|..||.....|::.|.:|:|
Human  1076 VMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR 1140

  Fly   129 PSI-----IFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLEKG-N 187
            .:.     :.|   :..:.|.|.|.:||     |..||       ::.|......:||::.|. |
Human  1141 SACLMTTQLIC---KLLRSREAAAAVDV-----RTWPL-------ILDTDDLPKKRPAQICKPCN 1190

  Fly   188 DQTLAIL-CSSGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNT------------------- 232
            ..|||.| .|..|||            :|||        |:.||..
Human  1191 PDTLAYLDFSVSTTG------------MLAG--------VKMSHAATSAFCRSIKLQCELYPSRE 1235

  Fly   233 ----LDWITGL------LTTITSGVFSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMI 287
                ||...||      |.::.||..|.....::...:||..|..:.:|||..|....|.|.|..
Human  1236 VAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCT 1300

  Fly   288 NCPDFET-------CDMSSLR-CYMFGGSRAALEVQKGIRSRLSHD------------------- 325
            .....:|       .|:|.:| |.:....|..:.:.:.. |:|..|
Human  1301 KGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSF-SKLFKDLGLHPRAVSTSFGCRVNLA 1364

  Fly   326 -CLQ------------------FVYGFTELGAMATINCHFDEKTGS--------VGQLVNGLKMK 363
             |||                  .||  .::.|:........|: ||        .|:::.|:::.
Human  1365 ICLQPHRLWTLAEQGTSGPDPTTVY--VDMRALRHDRVRLVER-GSPHSLPLMESGKILPGVRII 1426

  Fly   364 IINDDGES-LGPDEIGEVCIMNNQHWSGY---YGNE---VETRNMRDSLG-----WYHSGDLGYM 416
            |.|.:.:. ||...:||:.:.:..:.|||   ||:|   .:..|.|.|.|     |..:|.||::
Human  1427 IANPETKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFL 1491

  Fly   417 ----------DRDGFLYIMDRKKEMLKYQNIMYYPNDIE-SVISEMPQVAEVCVFGIWSNIFGDE 470
                      :|...||::....|.::.:.:.|:|.||| |||.....|.|..|| .|:|:.
Human  1492 RRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVF-TWTNLL--- 1552

  Fly   471 AAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVD--DLQRSANGKTNRMANKAYFL 531
              ..||:..|||.||.|:|..|.:....::..:.|..|:||  .:..::.|:..||..:..||
Human  1553 --VVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFL 1613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	144/622 (23%)
		AFD_class_I	47..522	CDD:302604	141/599 (24%)
DIP2C	XP_011517730.1	DMAP_binding	<32..180	CDD:283995
		CaiC	377..968	CDD:223395
		Dip2	401..965	CDD:213273
		AMP-binding	1036..1520	CDD:278902	113/522 (22%)
		AFD_class_I	1053..1615	CDD:302604	145/606 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810