DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and zgc:158482

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001076488.1	Gene:	zgc:158482 / 100009650	ZFINID:	ZDB-GENE-070209-32	Length:	619	Species:	Danio rerio

Alignment Length:	528	Identity:	119/528 - (22%)
Similarity:	204/528 - (38%)	Gaps:	106/528 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 EGTVLTRGELLANAMRLA-SYMRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYD 116
            ||..||..:....:.|:| :.:|..|:...|...:...|....:....|....|.|...||.:..
Zfish    75 EGQTLTYRDADRESNRIANALLRECGMRAGDTAALFITNQPAFILCWIALAKLGCACALLNTSIR 139

  Fly   117 RDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKI-------------VTMRNHPLDSIKIDE 168
            .|::.:.::..|.:          ||..|:|:|...:             |.|.......::...
Zfish   140 DDSLIRSFRCCRGA----------KVLIASADLQAAVQQVCVPLQQDGVCVLMMGMECSGMRSLS 194

  Fly   169 VVATPIEENFQPA--KLEKGNDQTLAILCSSGTTGTPKAVTITNSRHILAG-----NYHLTTADV 226
            ..|....:...||  :....|:.....:.:|||||.|||..||.:| :||.     :..:|..||
Zfish   195 RAAQESSDTAVPAAVRAHLTNNTPAVYIYTSGTTGLPKAAVITQTR-LLASLAVLPSIGVTHTDV 258

  Fly   227 QY----SHNTLDWITGLLTTITSG-------VFSTTRIIADNAFDPAFALRIIEEYKVTWTIQPP 280
            .|    .::|..::.|.:..:.:|       .||.:|.     :|...|      ::||......
Zfish   259 LYVTLPLYHTAGFLIGFMGCVETGSSMVLRRKFSASRF-----WDECRA------HEVTVVQYIG 312

  Fly   281 SSMALMINCPDFETCDMSSLRCYMFGGSRAALEVQKGIRSRLSHDCLQFVYGFTELGAMATINCH 345
            ..:..:.|.|........::|..:..|.||  :|.:....|.....::..|..|| |.:..:|
Zfish   313 EILRYLCNTPQRAVDQHHAVRLAIGNGLRA--DVWREFLQRFGQMEVREFYASTE-GNIGFLN-- 372

  Fly   346 FDEKTGSVGQLVNGLKMKI----INDDGESLGP--DEIGE----------VCIMNNQHWSGYYG- 393
            :..:.|:||::....:|.:    |..|.|...|  |..|.          :.:....|.:.:.|
Zfish   373 YTGRLGAVGRVSFLHRMAVHYALIQFDTEREEPVRDSSGRCVEVPKGQTGLLVSQITHMAPFVGY 437

  Fly   394 ----NEVETRNMRDSLG----WYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISE 450
                .:.|.:.:||...    :::||||..||:|.|||.:||..:..:::.......::..|:|.
Zfish   438 AHDEQQTERKRLRDVFRRGDVYFNSGDLMRMDQDNFLYFIDRVGDTFRWKGENVATTEVSDVLSL 502

  Fly   451 MPQVAEVCVFGIWSNIFGDE---AAAAVVKKLGSELEAQDVVD--------YVRSR--------- 495
            :..|||..|:|:.  :.|.|   ..|||..|.|:|.|.:.|.:        |.|.|
Zfish   503 LECVAEASVYGVC--VPGHEGRIGMAAVKLKDGAEFEQKQVFEHVSRLLPAYARPRFLRLQSSME 565

  Fly   496 TDSKYKQL 503
            ..|.:|||
Zfish   566 LTSTFKQL 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	119/528 (23%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	119/528 (23%)
zgc:158482	NP_001076488.1	PRK08279	24..619	CDD:236217	119/528 (23%)
zgc:158482	NP_001076488.1	AFD_class_I	76..609	CDD:302604	118/527 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930