Protein Alignment GluClalpha and Gabrp

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_112291.1
• Gene: Gabrp / 81658
• RGDID: 620532
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 150/489 - (30%)
• Similarity: 241/489 - (49%)
• Gaps: 96/489 - (19%)

  Fly    11 LYFASLCSASLA-------NNAKINFREKEKKVLD--QILGAGKYDARIRPSGINGTDGPAVVRV 66
            ||.|.:|...||       |...:.....:|..|.  :.|.|| |:..:||   |....|..:.:
  Rat     5 LYLAFVCLNLLAQRMCIQGNQFNVEVSRSDKLSLPGFENLTAG-YNKFLRP---NFGGDPVRIAL 65

  Fly    67 NIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTEANRV---WMPDLFFSNE 128
            .:.:.|||.|.:..|:|:..:..|::|||.||.|   :|. |..|| :|..|   |:||.:....
  Rat    66 TLDIASISSISESNMDYTATIYLRQRWTDPRLVF---EGN-KSFTL-DARLVEFLWVPDTYIVES 125

  Fly   129 KEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVF 193
            |:...|.:.:.|..||:|.||:|||::||:.|:.|.|:|..||:|.|.|.|::.|:|:..||:.|
  Rat   126 KKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190

  Fly   194 LWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCM 257
            .|..| |.|:.::||.|.::|::::.|....|:..||.|:.|.:....:|...|::::.|:|...
  Rat   191 SWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTF 255

  Fly   258 LVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVS-YTKAIDVWTGVCLTFVFGA 321
            ||::||||||:...:||||..:||||:|:|.|...|...|||..: :.|||||:.|:|.:|||||
  Rat   256 LVVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGA 320

  Fly   322 LLEFALVNYAS--------------RSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNAT 372
            |||:|:.:|:|              ....|..|:...::...:|.:..||::.:.|.::. |:.|
  Rat   321 LLEYAVAHYSSLQQMAVKDRGPAKDSEEVNITNIINSSISSFKRKISFASIEISGDNVNY-SDLT 384

  Fly   373 FAMASQFARGGGQQKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSK------- 430
            ...:.:|                                            ||..|.|
  Rat   385 MKASDKF--------------------------------------------KFVFREKIGRIIDY 405

  Fly   431 -------RIDVISRITFPLVFALFNLVYWSTYLF 457
                   .:|..|::.|||:|.|.|:.||:.|::
  Rat   406 FTIQNPSNVDRYSKLLFPLIFMLANVFYWAYYMY 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	149/485 (31%)
Gabrp	NP_112291.1	LIC	43..437	CDD:455710	140/447 (31%)
		LGIC_ECD	60..241	CDD:475126	65/185 (35%)