Protein Alignment GluClalpha and gabrg2

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_031754595.1
• Gene: gabrg2 / 779514
• XenbaseID: XB-GENE-5949005
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 447
• Identity: 142/447 - (31%)
• Similarity: 221/447 - (49%)
• Gaps: 84/447 - (18%)

  Fly    46 YDARIRPS-GINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY 109
            ||.::||. |:.    |.|:..:::|.||..::.:.|||::.:.|.:.|.|.||||:   ..:|.
 Frog   107 YDNKLRPDIGVK----PTVIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN---STIKV 164

  Fly   110 LTLTE--ANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPL 172
            |.|..  ..::|:||.||.|.|:...|.|..||..:||:.:|.|||::|:::...|.:.|..:|:
 Frog   165 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPM 229

  Fly   173 DRQICSLRMASYGWTTNDLVFLWKEGDPVQV--VKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLK 235
            |...|.|..:|||:...::::.||... |:|  |::..|.:|:...........||.:|:|..:.
 Frog   230 DEHSCPLEFSSYGYPKEEIIYQWKRSS-VEVGDVRSWRLYQFSFVGLRNTTEEVKTTSGDYVVMT 293

  Fly   236 VDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPP 300
            |.....|...|:.||.||||.::|::||||||:::.|||||.|||:||:|||.|.::....|||.
 Frog   294 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPK 358

  Fly   301 VSYTKAIDVWTGVCLTFVFGALLEFALVNY--ASRSGSNKANMHKENMKKKRR------------ 351
            |||..|:|::..||..|||.||:|:..::|  ::|..|      |:..|||:.
 Frog   359 VSYVTAMDLFVSVCFIFVFAALMEYGTLHYFVSNRKPS------KDKEKKKKNPLLWMFSFKAPT 417

  Fly   352 ----------------DLEQASLDAASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALE 400
                            .|::...:...:.||....|:|....:..|.|..     ||.
 Frog   418 IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAW-----RHG------- 470

  Fly   401 KRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYLF 457
                 .:|::..|                  ||..|||.||..|.|||||||.:||:
 Frog   471 -----RIHIRVAK------------------IDSYSRIFFPTAFCLFNLVYWVSYLY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	140/443 (32%)
gabrg2	XP_031754595.1	LIC	99..502	CDD:455710	140/443 (32%)
		LGIC_ECD_GABAAR_G	120..301	CDD:349801	56/184 (30%)
		Cys-loop	220..234	CDD:349801	4/13 (31%)