Protein Alignment GluClalpha and gabrg1

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_009305483.1
• Gene: gabrg1 / 556202
• ZFINID: ZDB-GENE-141215-66
• Length: 454
• Species: Danio rerio
• Alignment Length: 444
• Identity: 141/444 - (31%)
• Similarity: 221/444 - (49%)
• Gaps: 70/444 - (15%)

  Fly    36 VLDQILGAGKYDARIRPS-GINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLK 99
            :|:::|..  ||.::||. |:.    |.|:...::|.||..:|.:.|||::.:.|.:.|.|.|||
Zfish    58 ILNKLLQG--YDNKLRPDIGVR----PTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLK 116

  Fly   100 FDDIQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACP 164
            |:... :|..|......::|:||.||.|.::...|.|..||..:|::.||.|:|::|:::...|.
Zfish   117 FNSSM-KLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECY 180

  Fly   165 MNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFL-------TDYC 222
            :.|..:|:|...|.|..:|||:..|::.:.|:... |:|....:   :.|.:|.       :|..
Zfish   181 LKLHNFPMDEHSCPLEFSSYGYPKNEIQYRWQRRS-VEVADQRY---WRLYQFAFVGLRNSSDVA 241

  Fly   223 NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTM 287
            |  |.:|||..:.:.....|...|:.||.||||.|:|::||||||:::.|||||.|||:||:|||
Zfish   242 N--TQSGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTM 304

  Fly   288 ATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNK----ANMHKENMKK 348
            .|.::....|||.|||..|:|::..||..|.|.||:|:..::|.:.:..||    ::..|.:|..
Zfish   305 TTLSTISRKSLPKVSYVTAMDLFVSVCFIFTFAALMEYGTLHYFTSNRQNKKTKSSHAQKPSMVN 369

  Fly   349 KRRDLEQASL----------DAASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALEKRL 403
            .|.......:          |.|.:.||.....:|.......|.|..:             |.|:
Zfish   370 IRPGTSLLQMNNIAPYHEDDDYAYECLDGKDCTSFFCCFDDCRSGAWR-------------ENRM 421

  Fly   404 QCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYLF 457
              .||:                    .:||..|||.||..|.|||||||..||:
Zfish   422 --HVHV--------------------SKIDSYSRIFFPTAFGLFNLVYWIGYLY 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	139/440 (32%)
gabrg1	XP_009305483.1	LIC	58..451	CDD:455710	139/440 (32%)
		LGIC_ECD_GABAAR_G	79..260	CDD:349801	54/187 (29%)
		Cys-loop	179..193	CDD:349801	4/13 (31%)