DRSC/TRiP Functional Genomics Resources

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Protein Alignment GluClalpha and nAChRalpha2

DIOPT Version :9

Sequence 1:NP_001287408.1 Gene:GluClalpha / 42350 FlyBaseID:FBgn0024963 Length:463 Species:Drosophila melanogaster
Sequence 2:NP_524482.1 Gene:nAChRalpha2 / 42919 FlyBaseID:FBgn0000039 Length:576 Species:Drosophila melanogaster


Alignment Length:374 Identity:80/374 - (21%)
Similarity:149/374 - (39%) Gaps:85/374 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 ILYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSIS 74
            :|....||....||       ...|::.|.:|  ..|:..|||.. |.||   .|.|.:.:| :|
  Fly    29 LLVLLLLCETVQAN-------PDAKRLYDDLL--SNYNRLIRPVS-NNTD---TVLVKLGLR-LS 79

  Fly    75 KIDDVTMEYSVQLT---FREQWTDERLKFDDIQGRLKYLTLTE----ANRVWMPDLFFSNEKEGH 132
            ::.|:.::..:..|   ...:|.|.:.|:|..:    |..:||    :..:|:||:...|..:|.
  Fly    80 QLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSE----YGGVTELYVPSEHIWLPDIVLYNNADGE 140

  Fly   133 FHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTN----DLVF 193
            :....|....:..  .|.|:::.......:|.::::.:|.|:|.|.::..|  ||.:    ||..
  Fly   141 YVVTTMTKAILHY--TGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGS--WTYDGDQIDLKH 201

  Fly   194 LWKEGDPVQVVK---------------NLHLPRFTLEKFLTDYCNSKTNTGEYSCLK---VDLLF 240
            :.::.|....|:               .|.:|....||:             |.|..   .|:.|
  Fly   202 ISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKY-------------YPCCAEPYPDIFF 253

  Fly   241 ----KREFSYYLIQIYIPCCMLVIVSWVSFWL--DQGAVPARVSLGVTTLLTMATQTSGINASLP 299
                :|:..:|.:.:.|||..:..:|.:.|:|  |.|   .:::|.::.||:.......|:..:|
  Fly   254 NITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSG---EKIALCISILLSQTMFFLLISEIIP 315

  Fly   300 PVSYTKAIDVWTGVCLTFV-----FGALLEFALVNYASRSGSNKANMHK 343
            ..|....:   .|..|.|.     ...::...::|...|    |.:.||
  Fly   316 STSLALPL---LGKYLLFTMLLVGLSVVITIIILNIHYR----KPSTHK 357

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GluClalphaNP_001287408.1 LIC 3..455 CDD:273305 80/374 (21%)
nAChRalpha2NP_524482.1 LGIC_ECD_nAChR_proto_alpha-like 44..263 CDD:349832 52/246 (21%)
LIC 47..544 CDD:273305 74/349 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR18945
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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