Protein Alignment GluClalpha and SecCl

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 141/515 - (27%)
• Similarity: 234/515 - (45%)
• Gaps: 81/515 - (15%)

  Fly     7 FWAILYFASLCSASLANNAKINFREKE------------KKVLDQILGAGKYDARIRPSGINGTD 59
            ||..|    :...|:..:..:...|:|            .:::.::....:||...||...: :|
  Fly    10 FWITL----ILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYD-SD 69

  Fly    60 G---PAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKF------DDIQGRLKYLTLTEA 115
            |   |.||:..|:|..:..::...:::.:....:.::.|:||.:      |:|.|: |:|    :
  Fly    70 GKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQ-KHL----S 129

  Fly   116 NRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLR 180
            .|:|:|.:||:||:|.........:|...:.|.|:|:.|.|:..:|.|.||.:.:|.|:|.||..
  Fly   130 ERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTV 194

  Fly   181 MASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKF-------LTDYCNSKTN--TGEYSCLKV 236
            :.|:.:.|:||:..|:...|:.....:.|..:.:.:|       .:|..|.:..  .|.||.|..
  Fly   195 LESWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSF 259

  Fly   237 DLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPV 301
            .:..|||..:||:..|:|..|:|.:|||||||...|.|.|:.||.:|:|:..|.:|..:.:||.|
  Fly   260 TVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKV 324

  Fly   302 SYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMK----------KKRRDLEQA 356
            ||.|..:||...|..|:||:|:|||.||...|...| ..:.|.|.|          ..||.: ..
  Fly   325 SYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKEN-IELKKVNSKYIIKSTLTPRPARRQI-GG 387

  Fly   357 SLDAASDLLDTDSNATFAMASQFARGG------GQQKPLVRHPGDPLALEKRLQCE--------- 406
            ||...|......|......:::..|.|      |....|..||..|:.   |.:|.
  Fly   388 SLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPII---RTECAEADTVSICS 449

  Fly   407 --------VHMQAPKRPNCCKTWLSKFPTR-SKRIDVISRITFPLVFALFNLVYWSTYLF 457
                    |.:...|: :...|:.:..|.. :..||..||..||.:|..||.:|| |:::
  Fly   450 ARTNNDHIVDVDKDKK-DTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYW-TFVY 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	140/511 (27%)
SecCl	NP_648984.2	LIC	43..505	CDD:455710	134/474 (28%)