Protein Alignment GluClalpha and nAChRbeta1

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 464
• Identity: 95/464 - (20%)
• Similarity: 174/464 - (37%)
• Gaps: 123/464 - (26%)

  Fly    10 ILYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSIS 74
            :|...||.|||         .::|:.|.|...|   |:..|||  :........||..:....:.
  Fly    15 VLVAFSLVSAS---------EDEERLVRDLFRG---YNKLIRP--VQNMTQKVGVRFGLAFVQLI 65

  Fly    75 KIDDVTMEYSVQLTFREQWTDERLKFDDIQ-GRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIM 138
            .:::........:..|..|.|.:|::|:.. |.:..|.| ..::||.||:...|..:|::.....
  Fly    66 NVNEKNQIMKSNVWLRLVWYDYQLQWDEADYGGIGVLRL-PPDKVWKPDIVLFNNADGNYEVRYK 129

  Fly   139 PNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTN-------------- 189
            .||.  |:|.|.||:........:|.:::..:|.|:|.|.::..|  ||.|
  Fly   130 SNVL--IYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGS--WTFNGDQVSLALYNNKNF 190

  Fly   190 -DLVFLWKEG--DPVQVVKNLHLPRFTLEKFLTDY---CNSKTNTGEYSCLKVDLLFKREFSYYL 248
             ||...||.|  |.::|           ..:|..|   .|..|.|.    :...::.:|:..:|.
  Fly   191 VDLSDYWKSGTWDIIEV-----------PAYLNVYEGDSNHPTETD----ITFYIIIRRKTLFYT 240

  Fly   249 IQIYIPCCMLVIVSWVSFWLDQGAVPA----RVSLGVTTLLTMATQTSGINASLPPVSYTKAIDV 309
            :.:.:|..::..:..:.|:|     ||    :|:||::.||::......::..|||.|....: :
  Fly   241 VNLILPTVLISFLCVLVFYL-----PAEAGEKVTLGISILLSLVVFLLLVSKILPPTSLVLPL-I 299

  Fly   310 WTGVCLTFVFGA---LLEFALVNYASRS-GSNKANMHKEN-----------MKKKRRDLEQASLD 359
            ...:..||:...   |:...::|:..|. .:::..|:..:           ||:.|:...:..::
  Fly   300 AKYLLFTFIMNTVSILVTVIIINWNFRGPRTHRMPMYIRSIFLHYLPAFLFMKRPRKTRLRWMME 364

  Fly   360 AASDLLDTDSNATFAMASQFARGGGQQKPLVRHP--GDPLALEKRLQC--------------EVH 408
            ..                      |...|...||  |.|..|.|.:..              ::|
  Fly   365 MP----------------------GMSMPAHPHPSYGSPAELPKHISAIGGKQSKMEVMELSDLH 407

  Fly   409 MQAPKRPNC 417
                 .|||
  Fly   408 -----HPNC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	95/464 (20%)
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	95/464 (20%)
		Neur_chan_LBD	28..236	CDD:280998	53/232 (23%)
		Neur_chan_memb	243..498	CDD:280999	35/202 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447361
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030