DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GluClalpha and CG12344

DIOPT Version :9

Sequence 1:	NP_001287408.1	Gene:	GluClalpha / 42350	FlyBaseID:	FBgn0024963	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_001286298.1	Gene:	CG12344 / 36145	FlyBaseID:	FBgn0033558	Length:	449	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	131/468 - (27%)
Similarity:	210/468 - (44%)	Gaps:	72/468 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYS 84
            |.|..|.:|:..|.:.||..     .|...|||....|:  |.:|..:|||..|:.|:...|::.
  Fly    23 SEATEAHMNYTAKPRVVLPP-----NYVKEIRPPSKKGS--PVIVDFSIFVVDINSINVEDMDFR 80

  Fly    85 VQLTFREQWTDERLKF-DDI--QGRLKYLTLTEA--NRVWMPDLFFSNEKEGHFHNIIMPNVYIR 144
            |.:...::|.:.||:. |||  :|. .|:||...  ...|.||.:|.|.|......:......:.
  Fly    81 VDMFIHQRWLESRLEIPDDIFEEGD-DYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVT 144

  Fly   145 IFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHL 209
            ::.|.:|.|:.|:...:||.|..:|||:|.|:|.:.:.|:......:...|.:.. |.:...|.|
  Fly   145 LYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSG-VTLNPELKL 208

  Fly   210 PRFTLEKFL-----TDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLD 269
            .::.|.:.|     ..|...|  .|.:|.|.|...|:|:..::|||.:.|..::|::||.||||.
  Fly   209 LQYNLGQPLELEESDGYMPEK--VGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLG 271

  Fly   270 QGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRS 334
            ..|:|.||:|.||.:||:.|..:|  |.:|||:|.||:|:|...|:..||.||.||.:|......
  Fly   272 LDAIPGRVTLLVTCMLTLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQ 334

  Fly   335 GSNKAN-------MHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQKPLVRH 392
            ...:.|       |...||:|                      ...|..:.:..|..:.:...:.
  Fly   335 YQYQVNRIPKVLPMRISNMEK----------------------GQCATVASWEGGAVRSRKATQT 377

  Fly   393 PGDPLALEKRLQCEVHMQ---APKRPNCCKTWLSKFPTRS---------KRIDVISRITFPLVFA 445
            |..|        .:..:|   .|.:|...::.||...|.:         :.||.:||..||::|.
  Fly   378 PTTP--------GQTSLQGNGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFF 434

  Fly   446 LFNLVYWSTYLFR 458
            :|.|:||...|.:
  Fly   435 VFVLLYWPILLMK 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	130/463 (28%)
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	128/460 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010