Protein Alignment GluClalpha and nAChRalpha5

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 373
• Identity: 90/373 - (24%)
• Similarity: 153/373 - (41%)
• Gaps: 74/373 - (19%)

  Fly     2 GSGHYFWAILYF-----ASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGP 61
            |...:.|..|..     |.:|.|..          .||::|..:|  ..|:...||. :|.:| |
  Fly   287 GLNKHSWIFLLIYLNLSAKVCLAGY----------HEKRLLHDLL--DPYNTLERPV-LNESD-P 337

  Fly    62 AVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQ-GRLKYLTLTEANRVWMPDLFF 125
            ..:...:.:..|..:|:........:..:.:|.|..|:::... |.:|.|.: ..:|:|.||:..
  Fly   338 LQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRI-PPHRIWKPDVLM 401

  Fly   126 SNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTN- 189
            .|..:..|......||.:|  .|||.||.........|.:::..:|.|.|.|.::..|  ||.:
  Fly   402 YNSADEGFDGTYQTNVVVR--NNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGS--WTYDG 462

  Fly   190 ---DLVFLWKE--GDPVQVVKN-----LHLPRFTLEKFLTDYCNSKTNTGEYSCLK---VDLLF- 240
               ||. |..|  ||....|.|     |.:|             .|.|...|:|..   :|:.|
  Fly   463 FQLDLQ-LQDETGGDISSYVLNGEWELLGVP-------------GKRNEIYYNCCPEPYIDITFA 513

  Fly   241 ---KREFSYYLIQIYIPCCMLVIVSWVSFWL--DQGAVPARVSLGVTTLLTMATQTSGINASLPP 300
               :|...||...:.|||.::..::.:.|.|  |.|   .::|||||.||::....:.:..::|.
  Fly   514 IIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSG---EKLSLGVTILLSLTVFLNMVAETMPA 575

  Fly   301 VSYTKAIDVWTGV---CLTFVFGA--LLEFALVNYASRSGSNKANMHK 343
            .|  .|:.: .|.   |:.|:..:  :....::||..|:    |:.|:
  Fly   576 TS--DAVPL-LGTYFNCIMFMVASSVVSTILILNYHHRN----ADTHE 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	89/372 (24%)
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:455710	84/337 (25%)